2.8 & 2.9 Protein Digestion

Question 0

Name the Non-Essential Ketogenic AA

Answer 0

NONE

Question 1

Name the ketogenic Essential AA

Answer 1

Leucine and Lysine

Question 2

Name the Glucogenic Essential AA

Answer 2

Histidine, THreonine, Methionine and Valine

Question 3

Name the Glucogenic and Ketogenic Essential AA

Answer 3

Isoleucine
Tryptophan
Pheynlalanine

Question 4

Name the Non essential Glucogenic and Ketogenic AA

Answer 4

Tyrosine

Question 5

What is ketogenic?

Answer 5

An amino acid that is degraded to Acetyl-CoA or Oxaloacetate.
Cannot be converted to glucose

Question 6

Role of HCl in protein digestion

Answer 6

Reduces pH to 1-2 which allows denaturation of dietary proteins

Question 7

What activates Pepsin?

Answer 7

Low pH and other active autoactivate pepsin as well

Question 8

Cholescystokinin is stimulated how in protein digestion and what are its function

Answer 8

It is stimulated by protein leaving the stomach
It stimulates release of pancreatic enzymes
It stimulates release of bile
It stimulates slow gastric empyting

Question 9

Role of Secretin in Protein digestion

Answer 9

Activates release of bicarbonate solution from pancreas to neutralize the pH of intestine

Question 10

What is the role of Enteropeptidase?

Answer 10

To convert trypsinogen to its active form trypsin

Question 11

T or F, Pancreatic enzymes are released into small intestine as zymogens

Answer 11

True

Question 12

What catalyzes Pepsinogen –> Pepsin

Answer 12

Low pH or other active pepsin

Question 13

What is the role of pepsin

Answer 13

Degrade large peptide fragments and some free amino acids

Question 14

What catalyzes Chymotrypsinogen –> CHymotrypsin

Answer 14

Tryspin

Question 15

What substrates does chymotrypsin act on?

Answer 15

Aromatic Amino Acids

Question 16

What does Trypsin digest?

Answer 16

Arginine and Lysine residues

Question 17

Elastase has substrate specificity for what?

Answer 17

Hydrophobic Amino acids

Question 18

What are the major end products of protein digestion?

Answer 18

Free Amino Acids
Dipeptides
Tripeptides

Question 19

How are dipeptides and tripeptides transported across intestinal cell?

Answer 19

By using an H+ symporter

Question 20

How are Free Amino Acids transported into intestinal cell?

Answer 20

Using a Na Symporter

Question 21

How are all amino acids taken up by the capillary?

Answer 21

By using a Na Symporter

Question 22

What is Ubiquitin?

Answer 22

It is a marker that tags proteins for degradation by the proteasome

Question 23

T or F, Few Amino Acids are reincorporated into new proteins within the body

Answer 23

False, Most amino acids are.

Question 24

What are the three determinants of Protein longevity

Answer 24

Oxidation PEST Sequences Amino Terminal Residues

Question 25

What is the significance of Amino Terminal residues?

Answer 25

Some have high stabalizing residues while others have destabalizing. This determines the longevity of the AA

Question 26

What are the 4 PEST Sequences

Answer 26

Glutamate Proline Serine Threonine