Topic 9: Integumentary System - Epidermis Flashcards

1
Q

What does the integumentary system consist of? (4)

A
  • skin
  • hair, nails, glands
  • sense receptors (nervous)
  • muscles
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2
Q

What are the two skin layers?

A

epidermis and dermis

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3
Q

The upper layer of the skin is ____

A

epidermis

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4
Q

The lower layer of the skin is ____

A

dermis

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5
Q

The layer below the skin is ___

A

hypodermis

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6
Q

What kind of tissue specifically is the epidermis layer?

A
  • stratified squamous epithelium from ectoderm
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7
Q

Is epidermis vascular?

A
  • no, since it is made up of epithelium tissue
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8
Q

What are strata (layers) of epidermis based on skin types? (5)

A
  • stratum basale
  • stratum spinosum
  • stratum granulosum
  • stratum lucidum
  • stratum corneum
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9
Q

How many rows of cells does the stratum basale have?

A
  • one row of cells
    note that these are more cuboidal
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10
Q

What are the two cell types in stratum basale?

A
  • keratinocytes
  • melanocytes
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11
Q

What is the function of keratinocytes? (3)

A
  • undergo mitosis
  • make keratin (tough protein)
  • migrate to surface as new cells produced in basale
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12
Q

What is the function of melanocytes?

A
  • produce pigment (melanin) for UV light protection
    ex. sunburns, wrinkles (collagen damage), cancer (DNA damage)
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13
Q

How do melanocytes affect our skin colour?

A
  • we all have the same relative number of melanocytes, but cells produce different amounts/shades of melanin
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14
Q

What is it called when no melanin is produced in a person?

A

albinism/achromia

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15
Q

What is visible in areas of thin skin?

A
  • blood (hemoglobin) is visible
  • gives skin pinkish tinge
    ex. nail bed/lips
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16
Q

What type of activity occurs in the stratum spinosum? (2)

A
  • limited cell division
  • keratinocytes bound together with many desmosomes
17
Q

What activity occurs in the stratum granulosum? (3)

A
  • contains dark staining gramules
  • produces lamellar granules (water-sealant)
  • transitional, where epidermal cells undergo apoptosis
18
Q

What type of cells are in stratum lucidum? (2)

A
  • flat, dead (too far from blood supply)
  • visible ONLY in thick skin
19
Q

What type of cells are in stratum corneum? (2)

A
  • 20-30 layers of flat dead cells filled with keratin (tough protein), surrounded by waterproofing glycolipid to prevent water loss
  • shed and replaced from below