Unit 1: Cytology Flashcards
Plasma membrane
creates two cellular environments
keeps things inside, keeps things from escaping, keeps things outside, has proteins to transport
-phospholipid bilayer
-proteins
lipid bilayer
2 layers
-hydrophilic: heads faces ECM and ICM
-hydrophobic: tails face each other
backbone
proteins in membrane
integral- span whole bilayer
peripheral- on ECM or ICM
glycolcalyx
sugar coat around plasma membrane
allows cells to recognize each other, what is friend or foreign
cytoplasm
cytosol/organelles
organelles
cytoplasm, nucleus, golgi, centriole, ribosomes, rER, sER, lysosome, cytoskeleton, mitochondria, vesicles
nucleus
envelope, pores, chromatin
transcription
occurs in the nucleus, RNA polymerase unzips the double helix DNA and copies it into a new strand of mRNA
translation
mRNA exits out of nuclear pores, meets up with ribosome in the cytoplasm
is read in codons, amino acid is matched to every codon
chain is made and pushed into the lumen
Protein production process
transcription
translation
lumen to rER
protein packed into transport vesicles and buds from ER
transport vesicles unloads protein to first level of Golgi
Golgi modifies protein structure/packages protein into vesicle
Golgi vesicle containing finished protein pinches off and forms a secretory vesicle
proteins released by exocytosis
Fates of a protein
secreted as hormones
lysosomes- organelle storing enzymes that will eat other organelles
plasma membrane
organelles
mitochondria, ribosomes, endoplasmic reticulum, Golgi, lysosomes
membrane permeability
how easy or difficult it is for something to pass through the membrane
freely permiable
easy to flow down concentration gradient (high to low)
passive transport
flowing down the concentration gradient using diffusion or facilitated diffusion (channel or carrier mediated)
active transport
travelling against the concentration gradient
ATP
receptor
binds to chemical messengers such as hormones sent by other cells
gated channel
channel that opens and closes to allow solutes through only at certain times