NUCLEIC ACID CHEMISTRY I Flashcards
two types of nucleic acids
deoxyribonucleic acid
ribonucleic acid
monomers of a polymeric nucleic acid
nucleotide
nucleotides (monomer) connected by _____________ bonds to form nucleic acid (polymer)
phosphodiester bonds
sugar puckering
prevalent in RNA and a form of DNA
produces shorter phosphate-phosphate distance resulting in a more compact helical conformation
C3 pucker
sugar puckering
in B-form DNA
C2 endo
purines
adenine guanine
pyrimidine
cytosine
thymine
uracil
a base linked to a sugar without a phosphate group
___________ are named by changing the nitrogen base ending to -osine for purines and -idine for pyrimidines
nucleoside
a ______– is named using the name of the nucleoside followed by the phosphate group
nucleotide
the base composition of DNA generally _______ from one species to another
varies
DNA specimens isolated from different tissues of the same species have the ______ base composition
same base
the base composition of DNA in a given species does not _________- with an organism’s age, nutritional status or changing environment
change
a sequence that is read the same way in either direction
palindrome
when the inverted repeat occurs within each individual strand of DNA
mirror repeats
hoogsteen pairing
triplex DNA