16. Linea alba. White sponge nevus Flashcards
1
Q
Other name for white sponge nevus
A
Canons disease
2
Q
White sponge nevus definition
A
- Rare genetic disease
- Aka canons disease
3
Q
Etiology of white sponge nevus
A
- Genetic
- Inherited as autosomal dominant trait
- Mutation of genes encoding keratin 4 and 13
4
Q
Clinical features of white sponge nevus
A
- Bilateral asymptomatic, white or grey lesions
- Multiple furrows with spongy texture
- Affects most commonly-> Buccal mucosa, floor of mouth, soft palate and labial mucosa
May also develop in vaginal, rectal and laryngeal mucosa
5
Q
Diagnosis of white sponge nevus
A
- History
- Clinical features
- Histological examination
6
Q
Laboratory tests for white sponge nevus
A
Biopsy and histological examination
7
Q
Differential diagnosis of White sponge nevus
A
- Leukoedema
- Chronic biting
- Leukoplakia
- Dyskeratosis congenita
pachyonychia congenita, focal palmoplantar and oral mucosa hyperkeratosis syndrome, and hereditary benign intraepithelial dyskeratos
8
Q
Treatment of White sponge nevus
A
No treatment required
9
Q
Linea alba definition
A
- Common alteration of buccal mucosa
- Usually bilateral
10
Q
Etiology of Linea alba
A
- Mechanical pressure/ irritation on buccal surface of teeth
- Sucking
11
Q
Linea alba clinical features
A
- Usually bilateral elevation
- Normal/slightly whitish coloured
- Normal consistency on palpation
- On buccal mucosa on occlusal level of teeth
- May be scalloped
- Seen often in obese individuals
12
Q
Diagnosis of Linea alba
A
Based on clinical features only
13
Q
Treatment of linea alba
A
No treatment required
