20. Erythroplakia. Oral radiation mucositis.

Question 1

Definition of Erythroplakia

Answer 1

• High risk
• Potentially malignant disorder of oral mucosa

Question 2

Etiology of Erythroplakia

Answer 2

• Not well known
• Tobacco, Alcohol, HPV 16 and 18

Question 3

Clinical features of Erythroplakia

Answer 3

• Asymptomatic, fiery red patch
• Smooth and velvety surface
• Located** buccal mucosa, palate, floor of the
  mouth, lateral aspects of the tongue, and retromolar area**
• Both sexes equally
• Malignant transformation(90%)

Question 4

Diagnosis of Erythroplakia

Answer 4

Biopsy and histologic examination

Question 5

Laboratory tests of Erythroplakia

Answer 5

Histologic examination

Question 6

Differential diagnosis of Erythroplakia

Answer 6

• Erythematous candidiasis
• Cinnamon contact stomatitis
• Early squamous cell carcinoma
• Erosive lichen planus
• Discoid lupus erythematosus

Question 7

Treatment of Erythroplakia

Answer 7

• Surgical excision
• Smoking and alcohol
  cessation

Question 8

Oral radiation mucositis definition

Answer 8

• Complication of radiation therapy
• For head and neck tumours

Question 9

Etiology of Oral radiation mucositis

Answer 9

Therapeutic radiation

Question 10

Clinical features of Oral radiation mucositis

Answer 10

• Acute and chronic
• Acute-first week-diffuse erythema and edema of oral mucosa
• Burning sensation of lip
• Erosions and ulcerations-covered with whitish yellow exudate
• Dry mouth, loss of taste and pain

Question 11

Diagnosis of Oral radiation mucositis

Answer 11

History and clinical features

Question 12

Differential diagnosis of Oral radiation mucositis

Answer 12

• Mucositis due to chemotherapy or stem cell transplants
• Drug reactions
• Erythema multiforme

Question 13

Treatment of Oral radiation mucositis

Answer 13

• High oral hygiene level
• Cessation of smoking or alcohol
• LA, topical corticosterioids and tacrolimus
• Oxygen releasing mouthwashes and saliva substitutes