4. Angioedema. Lymphoedema due to the radiation. Sarcoidosis. Mucoviscidosis.

Question 1

Definition of Angiodema

Answer 1

• Common allergic disorder
• Transient edema
• Dermis, subcutaneous tissues and submucosa

Question 2

Etiology of Angioedema

Answer 2

1. Hereditary
2. Acquired- food, medications, infections, LA

Question 3

Clinical features of Angioedema

Answer 3

• Edema of skin, mucous membranes and subcutaneous tissues
• Sudden onset
• Last 24-72 hours
• Sudden, painless smooth swelling
• Lips, tongue and soft palate

Question 4

Diagnosis of Angioedema

Answer 4

• History
• Clinical features
• Laboratory tests

Question 5

Laboratory tests for Angioedema

Answer 5

• Skin patch tests
• Serum immunologic tests
  *Molecular analysis-hereditary type

Question 6

Angioedema differential diagnosis

Answer 6

• Cheilitis granulomatosa
• Cheilitis glandularis
• Cellulitis
• Surgical emphysema
• Lymphedema
• Lymphangioma

Question 7

Treatment of Angioedema

Answer 7

• Removal of allergen
• Systemic corticosteroids/intramuscular epinephrine/Antihistamines in severe acute cases
• Hospital admission in life threatening cases

Question 8

Lymphedema due to radiation

Answer 8

• Effects depend on dose and duration of treatment
• Effects lips
• Painless,erythematous swelling
• Diagnosed based on history and clinical features

Question 9

Sarcoidosis

Answer 9

• Systemic granulomatous disease
• Lungs, lymph nodes, spleen, liver, CNS, bones, oral mucosa and salivry glands
• Mouth rarely involved
• Lip swelling may occur
• Red oral mucosal nodules with or without ulceration may be seen