[2] class3 Zaidi-transport Thru Membranes Flashcards Preview

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Flashcards in [2] class3 Zaidi-transport Thru Membranes Deck (77)
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61

Ex of antiporter

Sodium calcium exchanger

62

Ex of symporter

Lactose permease

63

Ex of uniporter

Mitochondrial Ca+ transporter

64

Uses a proton gradient generated by oxidation of fuel molecules to drive lactose and other sugars against [ ] gradient

Is a symporter

Lactose permease

65

Steps of lactose permease:

1-H+ out
2-lactose out
3-EVERSION
4-lactose in
5- H+ in
6-EVERSION

66

Polytopic membrane proteins are often:

Transporters

67

What 2nd structure are proteins that make up polytopic transport proteins in membrane

A helices

68

Sodium pump _____ and K+ pumps in ______

Out; in

69

uses ATP to change conformation for action to occur

Ptype atpase

70

If + ∆G what type of transport

Active transport

71

If -∆G what transport:

Passive: simple or facilitated diffusion

72

Why is P type called P type ATPase?

P=phosphate covalently bonded to protein during process that req's energy.

Ex: SERCA Na+/K+ pump / PMCA

73

Where does (Pi) phosphate bind on P type ATPase?

Aspartate residue

74

Inhibit the dephosphorylation of E2P state of the Na+/K+ pump

Digitalis

75

ATP binds to this point________ causing the active for of PMCA

btw 4 and 5 transmembrane domains

76

Abc transporter

MRSA

77

What position SERCA bind a phosphate thus activating its Ca++ transport capabilities

Asp 351