2.1.5 Flashcards
(64 cards)
What is the function of a plasma membrane?
barrier between the cell and it’s environment
What does the plasma membrane control?
the transfer of substances in and out of the cell
e.g water, ions , gases
What substances can pass through the plasma membrane?
water, ions, gases
What are the roles of membranes?
- compartmentalisation
- site of chemical reactions
- site of cell commuication / cell signalling
What are 2 key roles of membranes within organelles?
allows for concentration gradients to be established and maintained
Embedding of enzymes into the membrane
How do cells communicate?
signals like hormones bind to a specific receptor with a complimentary shape
What is cell signalling?
communication between cells
cell recognition / identification
cells working together
to trigger a response
How does insulin regulate blood sugar levels?
1) Insulin is produced from beta cells in the islet of langerhans in the pancreas in reponse to high blood sugar
2) Insulin binds to receptors in the cell memrane of cells such as muscle and liver cells
3)This triggers a response inside the muscle or liver cell causing glucose to be taken up from the blood and reducing blood sugar level
How do beta blockers work to reduce the chance of a heart attack?
beta blockers stop neurotransmitters binding to heart muscle therefore decreasing the chance of a heart attack
How does botox work?
botox blocks receptors in muscke fibres
stopping them from working and causing paralysis
How does HIV get into a cell?
mimicking the receptor sites for a white blood cell
What is the structure of a phospholipid?
2 fatty acids, 1 glycerol molecule and a phosphate group
What part of the phospholipid is hydrophobic?
Fatty acid chains
What part of the phospholipid is hydrophillic?
glycerol and phosphate
Why do the phospholipids arrange themselves in a bilayer at the cell surface?
hydrophillic heads oreintate themselves towards water and the hydrophobic tails orenitate themselves away from water
Intracellular fluid inside the cell and extracellular fluid outside the cell
Why is it called the fluid mosaic model?
fluid - components in the membrane move around, flexible
Mosaic - proteins embedded in the membrane give it a mosaic look
What are the functions of glycoproteins and glycolipids?
- Cell recogition / identification
- Cell signalling
- acts as antigens
- Acts as receptors
- Adhesion
What are the roles of the proteins in the fluid-mosaic model?
Carrier proteins transport large and polar substances
Channel proteins transport polar substances
What is the role of cholesterol in the membrane?
found between tails of phospholipids and regulates fluidity
more cholestrol - less fluid the membrane is
What factors affect membrane permeability?
- heat
- ethanol
- detergent / soap / washing-up liquid
How does heat affect membrane permeability?
- As temperature increases, phospholipids gain kinetic energy
- causes gaps to appear between phospholipids
- membrane becomes more permeable
- At high temperatures proteins in the membrane denature
How does ethanol affect membrane permeability?
- Alcohol dissolves the phospholipid bilayer
- the higher the alcohol concentration the more permeable the membrane becomes
How does detergent affect the membrane permeability?
Detergents dissolve the phospholipid bilayer making the membrane more permeable
What are the control variables in the beetroot experiment?
Mass / length of beetroot
Same species of beetroot
Same volume of water
All beetroot cylinders in water for the same time