Digoxin

Question 1

Digoxin- Name

Answer 1

Lanoxin

Question 2

Digoxin- Class

Answer 2

Cardiac Glycoside

Antidysrhythmic

Inotropic Agent

Question 3

Digoxin- MoA

Answer 3

Inhibits sodium/potassium pump, thereby increasing intracellular calcium levels

Positive inotropic effect, increases cardiac output

Decreases chronotropy and dromotropy; slows AV conduction

Question 4

Digoxin- Indications

Answer 4

AFIB/AFLU

Refractory SVT

Chronic CHF

Question 5

Digoxin- Contra

Answer 5

23 VV C

2nd and 3rd degree heart blocks

VFIB VTAC (unless due to CHF)

Use cautiously in patients who have already taken normal therapeutic dose

Question 6

Digoxin- S/E

Answer 6

Cardiovascular: bradycardia, AV blocks, dysrhythmias

Neurological: confusion

Question 7

Digoxin- Routes

Answer 7

IV, IO

Question 8

Digoxin- A DOSE

Answer 8

0.25 – 0.5 mg IVP

Question 9

Digoxin- P DOSE

Answer 9

not recommended

Question 10

Digoxin- EXTRAs

Answer 10

Precautions: AMI and renal failure

Need to decrease joules by 50% during cardioversion Pregnant or nursing woman Infants and children

May increase risk of dysrhythmias

Use with Beta Blockers may decrease actions of Digoxin

Digoxin has an extremely narrow therapeutic range; therefore, overdose/toxicity is common.

Signs of toxicity include severe sinus bradycardia, 2nd or 3rd degree heart block, VTAC, VFIB, hypokalemia, fatigue, weakness, n/v, loss of appetite, abdominal discomfort, headache and blurred or yellow-colored vision.