26-Motor7-BasalGanglia Flashcards Preview

Nsci > 26-Motor7-BasalGanglia > Flashcards

Flashcards in 26-Motor7-BasalGanglia Deck (62)
Loading flashcards...
1

Main components of basal ganglia (x4)

- neostriatum (caudate and putamen)
- globus pallidus
- subthalamic nucleus
- substantia nigra

2

The ___ receives major inputs to basal ganglia

neostriatum

3

caudate and putamen grouped together because

they are cytoarchitecturally similar nuclei

4

neostriatum:
primary output neurons

spiny neurons

5

neostriatum:
two subtypes of spiny neurons

- GABA/substance P (SP)
- Gaba/enkaphilin (ENK)

6

SP

substance P

7

ENK

enkephalin

8

neostriatum:
secondary neurons

aspiny neurons and interneurons

9

corticostriate pathway originates from ___

many cortical areas, especially premotor and primary motor cortex

10

corticostriate pathway terminates on ___ neurons in ___

spiny (both subtypes), neostriatum

11

corticostriate neurons are [excitatory/inhibitory]

excitatory (glutamate)

12

corticostriate information reflects [specific/nonspecific] cortical activity

specific

13

thalamostriate originates from ___ thalamic nuclei

midline

14

thalamostriate neurons are [excitate/inhibitory]

excitatory (glutamate)

15

thalamostriate information reflects [specific/nonspecific] activity

nonspecific, from reticular formation (arousal and attention)

16

striatum outputs to ___ and ___

GPi and GPe

17

direct pathway involves GABA/___ neurons to ___

SP, GP_i

18

indirect pathway involves GABA/___ neurons to ___

ENK, GP_e

19

globus pallidus (internal) is major [input/processing/output] system

output

20

GP_i projects to ___

VA/VL of thalamus

21

GP_i is mainly [excitatory/inhibitory]

inhibitory (GABA)

22

GP_e projects to ___

subthalamic nuclei (STh)

23

STh

subthalamic nuclei

24

GP_e in mainly [excitatory/inhibitory]

inhibitory (GABA)

25

[True/false]: there are feedback loops between cortex and basal ganglia

true

26

Two parts of substantia nigra

- pars compacta
- pars reticulata

27

striatonigral projection originates from ___

spiny neurons (primarily GABA/SP)

28

striatonigral projection is primarily [excitatory/inhibitory]

inhibitory

29

SNr is to ___ mvt as GP_i is to ___ mvt

eye, limb

30

SNr projects to (x2)

- VA/VL of thalamus
- brainstem