2nd sem: Hormones 1 Flashcards

1
Q

norepinephrine derived from

A

amines

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2
Q

TSH is derived from

A

polypeptide

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3
Q

estradiol is derived from

A

steroids

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4
Q

hormone that is produced in final form and used immediately

A

aldosterone

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5
Q

hormone produced in final form and stored in same cell

A

norepinephrine

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6
Q

hormone that is converted in the periphery

A

T3 & T4

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7
Q

hormone that is cleaved from large precursor into active hormone

A

Glucagon

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8
Q

group of hormones with short plasma half life

A

group 2 hormones

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9
Q

group of hormones that binds to intracellular receptors

A

group 1

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10
Q

group of hormones that second messengers carry out response desired

A

group 2

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11
Q

hormones that co-activators needed to activate target gene

A

group 1

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12
Q

estrogen belongs to what group of hormones

A

group 1

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13
Q

opioids belongs to what group of hormones

A

group 2

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14
Q

opioids mechanism of action

A

adenylate cyclase inhibition

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15
Q

parathyroid mechanism of action

A

adenylate cyclase activation

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16
Q

erythropoietin mechanism of action

A

tyrosine kinase

17
Q

GnRH mechanism of action

A

phosphoinositide turnover

18
Q

in the synthesis of polypeptide proteins, removal of the signal peptide produces the____

A

prohormone

19
Q

the receptor-hormone which binds to specific DNA sequences called hormone response elements are utilized by what particular types of hormones

A

lipid soluble hormones

20
Q

the enzyme system catalyzes the conversion of ATP to cyclic AMP

A

Adenylate cyclase

21
Q

GnRH stimulates the release of

A

LH and FSH

22
Q

the DNA binding domain is found in the

A

intracellular receptor

23
Q

group of steroids with 21 carbons

A

progesterone

24
Q

modification of the functional group on the D ring of the steroid nucleus would yield

25
Where are glucocorticoids synthesized in your adrenal cortex?
ZONA FASICULATA
26
What process does progesterone undergo to be converted into cortisol?
hydroxylation reactions
27
How many carbons does estrogens have?
18 carbons
28
From corticosterone, by action of aldosterone synthase, what group is added?
Carbonyl oxygen (happens in the zona glomerulosa)
29
when 17,20 lyase removes 2 carbons, what will be the type of hormone produced?
androgens (from 21 carbons -> 19 carbons)
30
Ano ang mas potent? Dihydrotestosterone Testosterone
DIHYDROTESTOSTERONE
31
What stimulates the zona glomerulosa to produce the specific hormones?
angiotensin II K+ ACTH
32
What is the active form of vitamin D?
1,25 cholecalciferol or CALCITRIOL
33
from precursor proteins and peripheral activation
T3 and DHT