VITAMINS REVAMPED

Question 1

folic acid antagonists are competitive inhibitors of this enzyme

Answer 1

folic reductase

Question 2

Test for vit b6 deficiency

Answer 2

tryptophan load test

Question 3

Vitamin needed in the conversion of

homocysteine 🡆 methionine

Answer 3

B9

B12

Question 4

major excretory form of vit c

Answer 4

oxalic acid

Question 5

if thiamine is deficient, what sugars will tend to accumulate in the blood and urine

Answer 5

ribose and xylulose

Question 6

people who are found of eating raw fish, clams and oysters may develop deficiency in what vitamine

Answer 6

thiamine vit b1

Question 7

macrocytic anemia WITHOUT neurological symptoms is a deficiency manifestation of

Answer 7

folic acid vit b9

Question 8

coenzyme of the major anaphlerotic reaction and conversion of glutamic acid to GABA

Answer 8

vitamin b6 pyridoxine

Question 9

involved in the synthesis of cholesterol and extramitochrondial lipogenesis

Answer 9

vit b5 pantothetic acid

Question 10

coenzyme of transammination reactions. needed in the fixation of CO2 at carbon 6 of the purine ring and needed in the activation of folic acid

Answer 10

vit b7 biotin

Question 11

is folic acid an energy releasing vitamin

Answer 11

nope

Question 12

form of folic acid that is involved in the catabolism of histidine

Answer 12

methyl FH4

Question 13

with defective bone mineralization, poor wound healing and abnormal collagen formation

Answer 13

scurvy

Question 14

coenzyme of vit12 is also called

Answer 14

5 DEOXYADENOSYLCOBALAMIN and biologic grignard reagent

Question 15

swelling of costochondral junction is a deficiency manifestation of

Answer 15

vit c

Question 16

patient with impaired cognitive abilities and peripheral neuropathy. also a chronic alcoholic and has not been eating well for several weeks. this patient most likely is deficient in

Answer 16

thiamine vit b1

Question 17

lactic acidosis develops in thiamine deficiency because

Answer 17

pyruvate can not be converted to acetyl COA

Question 18

THIS VITAMIN ACTS AS A COENZYME IN THE RATE LIMITING STEP IN HEME SYNTHESIS

Answer 18

b6 or pyridoxal phosphate

Question 19

🤢 3 key manifestations of pantothenic acid or b5 deficiency

Answer 19

easy fatigability, atrophy of the adrenal glands and anemia

Question 20

enzyme assayed to know the status of b6 pyridoxine in the body

Answer 20

aminotransferase

Question 21

exact role for vit c in collagen synthesis

Answer 21

coenzyme for hydroxylation of lysine and proline

Question 22

deficiency of this vitamin may lead to oxalate stone formation

Answer 22

vit b6 or pyridoxine

Question 23

enzyme assayed to determine status of riboflavin b2 in the body

Answer 23

glutathione reductase

Question 24

megaloblastic anemia is a deficiency manifested in

Answer 24

folic acid and cobalamin

Question 25

rosary beads on the chest is a deficiency manifestation of

Answer 25

vit C and D

Question 26

bone calcium-binding proteins require vitamin K for their synthesis

Answer 26

osteocalcin and bone matric GLA protein

Question 27

vitamins that becomes deficient if there is complete obstruction of the common bile duct

Answer 27

retinol, calcitriol, vitamin E and farnoquinone | -frec-

Question 28

vitamins that are excreted mainly by the kidneys

Answer 28

riboflavin and niacin

Question 29

enzymes that requires TTP as coenzyme

Answer 29

alpha ketoglutarate dehydrogenase and pyruvate dehydrogenase

Question 30

atrophy of germinal epithelium in males and increased susceptibility to infection and also with with bitots spots

Answer 30

vitamin A deficiency

Question 31

enzymes that need b2 as coenzyme

Answer 31

xanthine oxidase, glycerophosphate dehydrogenase, glutathione reductase and pyruvate dehydrogenase xo, gpd, gd, pd

Question 32

proteins that are needed in the transport of vit A thru plasma and to the cells

Answer 32

retinol binding protein and pre-albumin

Question 33

dermatitis is a deficiency manifestation of

Answer 33

Vit b6, and riboflavin

Question 34

pathways utilizing NAD as coenzyme

Answer 34

oxidative deamination and gluconeogenisis

Question 35

forms of vit A that regulate growth, development and tissue differentiation

Answer 35

All-trans-retinoic acid and 9 cis retinoic acid

Question 36

substances needed in the conversion of beta carotene to vit a

Answer 36

insulin, thyroid hormone, zinc, vitamin e

Question 37

drugs that may interfere with folate metabolism

Answer 37

anticonvulsants and oral contraceptives

Question 38

pathways where biotin is needed as coenzyme

Answer 38

fatty acid biosynthesis and beta oxidation of odd numbered fatty acids

Question 39

pathways that require pantothenic acid

Answer 39

krebs, cholesterole synthesis, porphyrin synthesis, extramitochondrial lipogenesis

Question 40

vitamins that are needed to prevent homocysteine in the body

Answer 40

⮞ B3 (niacin) ⮞B6 (P,P,P) ⮞ B9 (folic acid) ⮞B12 (cobalamine)

Question 41

synthesized by bacteria flora in the gut

Answer 41

⮞ Vit K | ⮞ B1,2,7,9,12

Question 42

Natural vitamins?

Answer 42

⮞ Vit D, K | ⮞ B1,2,7,9,12

Question 43

RBC maturation vitamin

Answer 43

Vit B12

Question 44

vitamin that regenerates vitamin E

Answer 44

VIT C

Question 45

Vitamin E enhances ______ 🡆 increase risk of bleeding

Answer 45

warfarin (anti-coagulant)

Question 46

processes of oxidation

Answer 46

1. gain O2 2. lose H+ 3. lose e-

Question 47

vitamin needed for conversion of | homocysteine 🡆 cysteine

Answer 47

VIT B6

Question 48

cysteine + homocysteine =

Answer 48

⮞ pyruvate ⮞ a-ketobutyric acid ⮞ cysteine

Question 49

``` Clinical manifestations of: ⮞ cheesy odor of breath ⮞ accumulation of isovaleryl coA ⮞deficiency: Isovaleryl coA DH ⮞ inborn error assoc. with Leucine ```

Answer 49

Isovaleric Acidemia

Question 50

HMG CoA (3-hydroxy-3-methylglutaryl coenzyme A) is derived from Leucine and why is it important?

Answer 50

⮞ It serves as link bet. lipid and protein metabolism ⮞ intermediate ng cholesterol synthesis ⮞ intermediate ng ketogenesis

Question 51

VIT E deficiency 🡆 fat malabsorption such as?

Answer 51

⮞ chronic pancreatitis ⮞ cystic fibrosis ⮞ abetalipoproteinemia

Question 52

``` B1 🡲 DECARBOXYLATION (transfer 2C units) B3 🡲 reduction-oxidation reactions B6 🡲 transamination B7 🡲 carboxylation B9 🡲 _______ ```

Answer 52

transfer of 1 carbon unit