Flashcards in  Pharma II Anti-Thrombotics Deck (22):
Contraindications for Beta Blockers
What can you give to prevent remodeling of the Left Ventricle
What do you give to reduce the risk of recurrent coronary artery thrombosis
Statin therapy should be started at a low dose or high dose?
Heparins biologic activity is dependent on?
Difference of LMWH compared to Unfractionated Heparin
Heparin inhibits: Thrombin, IXa and Xa
LMWH inhibits: Thrombin alone
Anti-Platelet Therapy commonly uses this drug
How should you take an Aspirin tablet?
Chewed or crushed quickly
Heparin alternative in PCI patients
Treatment of embolism, DVT, AF
Mechanism of Action
Inhibits synthesis of factors II, VII, IX, and X
Inhibits production of Vitamin K
An ideal fibrinolytic agent with a short half life that is recommended in the West
Inhibitors of Fibrinolysis
Mechanism of Action of Aminocaproic Acid
Competitive lysine inhibitor
Mechanism of Action of Aprotinin
Serine protease inhibitor
Examples of Direct Thrombin Inhibitors that bind to both catalytic sites and substrate recognition site
Small molecules that bind only at the thrombin active site
In case of Heparin Overdose you give?
Mechanism of Action of Aspirin
Irreversible Cyclooxygenase Inhibitor
(Specifically prevents the creation of Thromboxane A2)