5/15 Flashcards

(28 cards)

1
Q

opioid analgesics tx of right upper abdominal pain

A

contract smooth muscle in sphincter of oddi –> increased pressure in common bile duct and gall bladder

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2
Q

necrotizing enterocolitis

A

common GI emergency of newborn

bacterial invasion and ischemic necrosis of bowel wall-

x-ray shows pneumatosis intestinalis (air in bowel wall)

associated with prematurity

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3
Q

ecological study

A

uses POPULATION data

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4
Q

T-tubules function

A

uniform depolarization- synchronized contractions

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5
Q

location of femoral hernia

A

inferior to inguinal ligament

medial to femoral vein, lateral to pubic tubercle

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6
Q

which sinuses fill with blow to the eye?

A

orbital floor–> maxillary sinus

medial wall–> ethmoidal sinus

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7
Q

lateral ankle sprain due to…

A

inversion of plantar flexed foot–> anterior talofibular ligament

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8
Q

what does haemophilus need to grow

A

factor V (NAD+) and factor 10 (hematin)

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9
Q

majority of drug OD deaths caused by…

A

opioids (heroin, pain analgesics)

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10
Q

transpeptidase

A

PBP that cross-links peptidoglycan into bacterial cell wall

target of ceftriaxone

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11
Q

phentolamine vs phenoxybenzamine

A

both alpha antagonists

phentolamine- reversible

phenoxybenzamine- irreversible

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12
Q

what do you screen for in dipstick for early-stage diabetic nephropathy

A

albumin levels

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13
Q

how to treat open angle glaucoma

A

diminish aqueous humor production by ciliary epithelium- beta blockers (timolol), acetozolamide

increase outflow of aqueous humor- prostaglandin F2alpha, cholinomimetics

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14
Q

vit c def/ascorbic acid deficiency

A
gingivitis
perifollicular hemorrhages
myalgia
subperiosteal hematomas
petechiae
impaired wound healing
weak immune response
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15
Q

food poisoning by pufferfish

A

produce tetrodotoxin- binds voltage gated Na channels in nerves and cardiac tissue, preventing depolarization

dizzy, weak, paresthesia, diarrhea, N/V

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16
Q

heteroplasmy

A

coexistence of different versions of mitochondrial genomes in individual cell

17
Q

contracture

A

during wound healing- excess matrix metalloproteinases and myofibroblasts accumulate in wound margins

produce deformities of wound

18
Q

1st and 2nd most common bacteria of hemotogenous osetomyelities

A

1) staph aureus

2) strep pyogenes

19
Q

common causes of osteonecrosis

A
  • alcoholism
  • glucocorticoids
  • sickle cell disease
  • vasculitis
20
Q

Alkaptonuria

A

benign childhood disorder–> severe arthritis in adulthood

aut rec- homogentistic acid dioxygenase deficiency- cant metabolize tyrosine

pigment deposits in connective tissue (eg. blue-black in sclera and ear cartilage; in joints causing ankylosis; black urine)

21
Q

locations of hematogenous osteomyelitis in adults vs kids

A

kids- metaphysis of long bones

aults- vertebral body

22
Q

serum sickness

A

circulating immune complexes

fever, pruritic rash, arthralgias,

fibrinoid necrosis, neutrophil infiltrate

23
Q

drugs that increase risk for osteoporotic fractures

A
PPIs
Glucocorticoids
unfractionated heparins
anticonvulsants that increase cyp450 (phenoarbital, phenytoin, carbamazepine)
aromatase inhibitors, GnRH agonists
24
Q

which arteries do polyarteritis nodosa spare

A

pulmonary and bronchial artery

25
which arteries that branch to splenic artery are prone to ischemia
short gastric arteries due to poor anastamoses
26
lesion in what would give contralateral homonymous hemianopsia and a defect in pupillary light reflex
optic tract
27
why cant EBV and CMV be treated as well with acyclovir?
dont produce the same thymidine kinase as herpes to phosphorylate the guanosine analog
28
bluish neoplasms under nail bed
- subungual melanoma | - glomus tumor- neurovascular thermoregulation