Rx Wrongs

Question 1

Order of conduction velocity from fastest to slowest

Answer 1

Purkinje–>His–>AV

Question 2

Dialtizem MOA

Answer 2

CCB- nondihydropyridines- prolong PR interval-inhibit voltage gated Ca channels

Question 3

SCID enzyme defect

Answer 3

adenosine deaminase- purine salvage pathway- DNA synthesis for T and B cells

Question 4

Amiodarone MOA and Tx

Answer 4

MOA: Class III- block K+ channels to prolong repolarization

Tx: Pulmonary fibrosis, hepatotoxicity, hypo/hyperthryoidism

Question 5

Skin condition in Rheumatic Fever

Answer 5

erythema marginatum

Question 6

Wilms Tumor Chromosome number

Answer 6

Chromosome 11

Question 7

Meckel’s diverticulum epidemiology

Answer 7

2 rule: 2% population, 2x more in boys, <2 yo, 2 feet from ileocecal valve, 2 inches long, 2 types of heterotopic mucosa

Question 8

Meckel’s diverticulum cause

Answer 8

failure of involution of vitelline duct–> intestinal obstruction

Question 9

ketoconzacole adverse reaction

Answer 9

liver dysfunction

Question 10

Rifampin

Answer 10

orange tint to secretions!

MOA: inhibit DNA-dep RNA pol –> RNA synthesis

Question 11

ethosuximide MOA

Answer 11

block T type calcium channels

Question 12

dermatome level of inguinal ligament

Answer 12

L1

Question 13

Marfan syndrome genetic defect

Answer 13

aut dom fibrillin 1

Question 14

which nerve innervates medial thigh (adductor muscles)?

Answer 14

obturator nerve

Question 15

metochlopramide

Answer 15

for gastroparesis in DM2. DA antagonist and increases LES tone

Question 16

wet, wacky, wobbly

Answer 16

normal pressure hydrocephalus- from increased CSF (enlarged ventricles) by tumors or from impaired reabsorption (super sagittal vein) from tumors or meningitis.

Question 17

1st branchial arch

Answer 17

M- mandible, malleus, sphenoMandibular ligament, musclles of mastication (temporalis, masseter, medial and lateral pterogoids)

Question 18

DiGeorge syndrome

Answer 18

defect of 3rd and 4th branchial pouches- no thymus

CATCH 22- cardiac defects, abnl facies, thymic hypoplasia, cleft palate, hypocalcemia due to microdeletion on chrom 22

Question 19

what drug will reverse the myelosuppression from methotrexate?

Answer 19

leucovorin

Question 20

Turners is associated with what heart defect

Answer 20

juxtaductal coarctation of aorta

Question 21

postductal coarctation of aorta

Answer 21

BP in upper extremities significantly higher than lower.
rib notching
high risk of bacterial endocarditis and cerebral hemorrhage

Question 22

cystic fibrosis main symptom buzzwords

Answer 22

steatorrhea, infertility, chronic persistent cough

pseudomonas infections

Question 23

Goodpasture associated with exposure to what?

Answer 23

hydrocarbon solvents

Question 24

lactobacillus is what type of bacteria

Answer 24

gram positive facultative anaerobes

Question 25

SSPE symtoms

Answer 25

1. demyelinate CNS--> personality changes, dementia (1 year) 2. myoclonus (3-12 months) 3. worsening dementia and ANS, and rigidity and flaccidity

Question 26

IL-2 helps treat

Answer 26

metastatic renal cell carcinoma

Question 27

autoimmune hemolytic anemia lab findings

Answer 27

positive Coombs test; high LDH, high indirect bilirubin, low haptoglobin

Question 28

which artery gets tangled in a fused horseshoe kidney?

Answer 28

inferior mesenteric artery

Question 29

which heart defect do patients with lyme disease have?

Answer 29

AV node block

Question 30

spermatids (N) and spermatogonium (2N) are located where in the seminiferous tubule? apical or basal?

Answer 30

Spermatogonia- begin meiosis at basal layer Spermatids- apical layer

Question 31

indirect versus direct hernia

Answer 31

indirect: congenital- processus vaginalis remains open direct: older men- weakness in abdominal wall

Question 32

alpha 1-antitrypsin deficiency leads to what two conditions?

Answer 32

panacinar emphysema and liver cirrhosis

Question 33

antibody associated with dermatomyoitis

Answer 33

anti-jo-1

Question 34

what can treat IBS

Answer 34

loperamide

Question 35

what two types of ectopic tissue is in meckel's diverticulum?

Answer 35

pancreatic and gastric

Question 36

what is the treatment regimen for Hodkin lymphoma?

Answer 36

Doxorubicin, Vinblastine, bleomycin, dacarbazine

Question 37

which organ is the last to begin hematopoiesis

Answer 37

bone marrow

Question 38

cremaster muscle is extension of what muscle?

Answer 38

internal oblique

Question 39

dressler syndrome

Answer 39

autoimmune fibrinous pericarditis--> pericardial frictional rub

Question 40

which CN controls jaw muscles?

Answer 40

5- V3

Question 41

down syndrome is a defect in which stage of cell division

Answer 41

Meiosis I- anaphase

Question 42

what is associated with a tracheoesophageal fistula?

Answer 42

polyhydromnios- cant swallow amniotic fluid