acronyms Flashcards
(20 cards)
what are the essential amino acids
ME, VAL, and LEUCI ISOLated HIS PHENdish LYS (lice) in THRE TRYs
what are the amino acids that can’t be degraded in maple syrup disease
I LoVe Maple Syrup
Isoleucine
Leucine
Valine
what are the coagulation factors who synthesis is dependent on vitamin K
diSCo started in 1972
proteins C and S
factors x, ix, vii, and ii
what are the symptoms of pellagra (B3/niacin deficiency)
3 Ds
Dermatitis, Dementia, and Diarrhea
what enzymes is vitamin B1 (thiamine) a cofactor for
ATP
Alpha-ketoglutarate dehydrogenase
Transketolase
pyruvate dehydrogenase
what does a deficiency in B1 cause
Ber1 Ber1
Beri beri:
dry=polyneuritis, muscle wasting (nerves)
Wet=dilated cardiomyopathy (heart)
what are the 2 C’s of Vitamin B2 (riboflavin) deficiency
Cheilosis and Corneal vascularization
what is B5 (pantothenate) a essential component of
“pantothena becomes COA” it rhymes
essential component of coenzyme A
what is a unique SE of B6 (pyridoxine) deficiency
“low on B6 and your body flicks”
Deficiency can cause convulsions
What does vitamin B7 (biotin) do
“Buy-a-tin of CO2”
cofactor for carboxylation reactions (enzymes with carboxylase in their name)
what can cause a B7 (biotin) deficiency
BIOtin
eggs are a BIOlogical product and the avidin in egg whites can bind eggs readily–think weight lifters
what are the two B vitamins used in redox reactions
“2 and 3 give hydrogen to me”
B2 (riboflavin)=part of FAD and FMN
B3 (niacin)=part of NAD+ and NADP+
what is the mutation in prothrombin gene mutation hyper coagulability
“Beverly hills 90210”
G20210A mutation–>G to A=Guanosine to adenosine
what clotting factors are deficient in hemophilia A and B
A= eight (their beginnings rhyme)
B=9 (benign)
what are the diseases that can cause target cells to appear on a peripheral smear
THAL
thallasemia
hemoglobin C disease
Asplenia
Liver disease
where does hematopoiesis take place in fetal development
Young Liver Synthesizes Blood
Yolk sac (3-8 weeks)
Liver (6 weeks-birth)
Spleen (10-28 weeks)
Bone marrow (18 to adult)
what are the 6 Ps of acute intermittent porphyria
defect in Porphobilinogen deaminase
Painful abdomen
Port Wine urine (dark colored)
Polyneuropathy
Psychological disturbances (heme precursors are neurotoxic)
Precipitated by drugs (barbiduates, seizure drugs, Rifampin, Metoclopramide)
what is the the way to remember porphyria cutanea tarda
PORphyria–>think of a Poor Hairy homeless IV Drug using Alcoholic with Blistering skin lesions and having Pissed himself
Hypertrichosis (hair growth)
associated with Alcoholics and Hep C
sx=Blistering cutaneous lesion
enzyme deficient=Uroporphyrinogen and tea colored Urine
what are the symptoms of lead poisoning
LEAD
Lead lines (dark blue lines on gums or hyperluscent lines on metaphysis of bones)
Encephalopathy
Abdominal colic and Anemia
Drops–foot and wrist
what are the tumors that can secrete erythropoietin and raise the hematocrit
Potentially Really High Hematocrit
Pheocromocytoma
Renal Cell Carcinoma
Hepatocellular carcinoma
Hemangioblastoma
