Flashcards in Adrenal disorders Deck (13):
Function of glucocorticoids
regulation of intermediary metabolism and immunity
Function and example of mineralcorticoids
Example of androgens
What binds Cortisol in plasma and what %
Effects of glucocorticoids
gluconeogenesis and glycogen synthesis in the fasting state.
Increase serum glucose levels/stimulate insulin release.
decreased muscle mass/weakness and thinning of skin.
↑ insulin secretion leading to ↑ in fat deposition.
Catabolic and anti-anabolic effects (Cushing's)
Adverse effects of systemic glucocorticoids short term
mood and behavioral changes
Adverse effects of systemic glucocorticoids long term
Three short to medium acting glucocorticoids
One long acting glucocorticoid
Adrenal glands produce too little cortisol
Insufficient levels of aldosterone.
Weakness, fatigue, weight loss, hypotension, hyper pigmentation,
Inability to maintain blood glucose level during fasting.
What is the tx for Adison's
20-30 mg of hydrocortisone daily
Supplement with salt-retaining hormone: Fludocortisone.
What is Cushing's syndrome
Chronic High levels of cortisol due to ACTH secreting tumor.
Buffalo hump, moon face, osteoporosis, hypertension.