Epilepsy Flashcards Preview

HD&T > Epilepsy > Flashcards

Flashcards in Epilepsy Deck (16):
1

What is a seizure

A finite episode

2

What are some common seizure precipitants

Metabolicand/orElectrolyteImbalance
• Stimulantorotherpro-convulsantintoxication
• Sedativeorethanolwithdrawal
• Sleepdeprivation
• ReductionorinadequateASDtreatment
• Hormonalvariations
• Stress
• Feverorsystemicinfection
• Concussion and/o rclosed head injury

3

What are the common causes of epilepsy in children

genetic susceptibility
Perinatal and neonata insults
Staus epilepticus
CNS infection
Trauma

4

What are the most common causes of epilepsy in the elderly

Neoplasm
CVA
Neurodegenerative disorders
Trauma
Status epilepticus

5

What are the most common causes of epilepsy in adults

Trauma
Neonatal GEFS+
status epilepticus

6

Simple partial seizure is characterized by
(must have all of these)

Localized focus
Minimal spread
Normal awareness, memory and consciousness
Short duration (60-90 sec)

7

Complex partial seizures are characterized by

Localized onset but spreads often bilaterally
Awareness, memory and or consciousness are lost during seizure
Manifestations vary with site of origin and degree of spread.
Longer duration (15 sec-3 min)

8

Secondary generalized seizure are characterized by

Begin as simple and/or complex partial seizures.
Tonic and clonic phases

9

What is tonic

Stiffening

10

What is clonic

jerking

11

Absence seizures are often observed by

Grade school teachers

12

What is the ideal ASD

Effective for the seizure type
Wide therapeutic index
No organ toxicity
No teratogenicity
No drug-drug interactions
Long half life
No protein binding (only the unbound drug is effective)
Water soluble
No active metabolites

13

Why are newer drugs safer

fewer drug-drug interactions

14

What are the main mechanisms of ASDs

Enhancement of GABA mediated inhibitions
Reduction of excitatory transmission
Modification of ionic conductances

15

What is the danger with Carbamazepine

Stevens-Johnson Syndrome

16

What is the only ASD that causes weight loss

Topiramate