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Flashcards in Psychopathology Deck (59):
1

What is DSM V

Diagnostic and Statistical Manual of Mental Disorders

2

What is axis 1

All psychological diagnostic categories except mental retardation and personality disorders:
Depression
Anxiety disorders
Bipolar
Autism
Anorexia/bulimia nervosa
Drug dependency

3

What is axis 2

Personality disorders and mental retardation:
Paranoid personality disorder
Schizoid personality dis
OC personality dis
Intelectual disabilities

4

What is axis 3

General medical conditions;
Acute medical conditions and
Physical disorders
Brain injuries (car accident) and other medical/physical disorders

5

What is axis IV

Psychosocial and environmental factors contributing to the disorder; stress

6

What is axis V

Global assessment of functioning
Children's global assessment scale

7

What is assessed in a Mental Status Examination MSE

Mood
Affect
Thought: Process, content, perception
Appearance
Cognitive function: define, cause ( org vs inorg)

8

What is affect

How you present yourself in appearance
carry yourself
communicate

9

What is thought

Process: organization, sequential
Content: relevant, insightful
Perception: understanding

10

What is appearance

Relevant
Hygiene
Aware of environment
Motivation

11

What are organic causes

Disease
Accident

12

What are inorganic causes

Molecular level

13

What are two types of Psychotic disorders

Psychosis
schizophrenia

14

What is psychosis

Impaired sense of reality.
Altered cognition and emotion.

15

What is the most commonly recognized psychiatric disease

schizophrenia

16

Schizophrenia background

$40 billion/yr
1% of pop
mostly poor urban

17

Schizo Sx

Remisions
Withdrawn
Abnormal thinking and speech
anhedonic--> suicide
Abnormal appearance --> worse in men
Men; late 20's and more aggressive
Wmn; late 20-30 and more aggressive
delusional
hallucinate
flat or labile emotions
difficulty filtering
lack of prepulsive inhibition; startle reflex

18

Schizophrenia requirements

sx that persist more than 6 months
deteriorating funtions
active psychosis
No drugs/trauma

19

What are the subtypes of schizophrenia

Disorganized
Catatonic
Paranoid (positive)
Residual (negative)

20

What is a disorganized schizophrenia

Blunted affect
incoherent
Not delusional
bizarre manorisms
grimacing

21

What is catatonic schizophrenia

non responsive but aware
rigid posturing

22

What is paranoid schizophrenia

POSITIVE; better response to meds
delusional
hallucinations
agressive
ucoperative

23

What is residual schizophrenia

NEGATIVE
socially withdrawn
flat effect
happens in later stages of disease
most difficult to treat

24

What are schizophrenia physical findings

↑ ventricular size
↓ corpus callosum
↓ frontal cortex blood
Do not yawn
Altered startle and accommodation

25

what is schizophrenia neurochemistry

DA mechanism
D2 excessive activity
5HT and glutamate contribute to negative sx

26

What is the genetic predisposition for schizophrenia

Monozygotic twins = 40-50 %
child of both parents = 30-40 %
child of one parent = 10-15 %
Dizygotic twin or sibling = 10 %
General population = 1%

27

Tx for schizophrenia

All block D2 and %HT2 receptors but increase D1 activity

28

What are side effects of schizophrenia drugs

anhedonia
sleepiness
restlessness
amenorrhea
weigh gain
Extrapyramidal side effects:
-Tardive dyskinesias
-parkinson's like tremors

29

What are two Phenothiazines and their properties

Chlorpromazine
Thioridizine
Least expensive
More sedation and weight gain; anticholinergic actions
less extrapeyramidal effects, more sedation
Antiemetic action; efective against vomiting and nausea

30

What is a butyrophenone and its properties

Haloperidol ( Haldol) ; widely used/genetic/inexpensive
High extrapyramidal side effects
no anticholinergic action or side effects

31

What are newer/atypical schizophrenia drug and prop

Clozapine
Serious agranulocytosis in 1-2 %
Quentiapine (seroquel)
Olanzepine (Zyprexa)
D2 and 5HT2A antagonists
little extrapyramidal side effects
most effective against negative effects

32

What is psychotic disorder

Stress related
delusions/halucinations
fast recovery

33

What is Schizoaffective

Might look bipolar
Tx will help distinguish it

34

What is cyclothymia

Minor bipolar
No gender bias

35

What is depression-dysthymia

Greater than 2 yrs
lower mood/anhedonia
6%
2:1 F/M
young adults

36

What RX is used for anxiety associated with everyday stress

Bupropion

37

What is the Rx for Severe acute anxiety panic attack

SSRI (Paxil)
Antidepressants (Venlafaxin)

38

What is the Rx for Phobic disorders

SSRI (Zoloft)

39

What are two types of ADHD/ADD

Predominantly hyperactive-impulsive
Predominantly inattentive

40

What are the Rx for ADHD

Amphetamines (adderall)
Methylphenidate (Ritalin)
Modafinil; fewer side effects, little abuse problem, non-stimulant

41

Sx of anorexia

relentless pursuit of thinness
distorted boy image
restriction of eating
osteoporosis
Muscle wasting
damage to heart
infertility
malnutrition
laxatives and diuretic

42

Bulimia sx

frequent bingeing and purging
normal weight
damage to esophagus and teeth
dehydration
turmoil-shame

43

What is the Tx for bulimia

mostly behavioral
fluoxetine and other antidepressants

44

What are two MAOI antidepressants

Phenelzine
Selegiline

45

What is good about tricyclic antidepressants

long half life/ single daily dose
Blocks the uptake of NE

46

What are the side effects of tricyclic antidepressants

xerostomia
H1 blockade
orthostatic hypotension
Withdrawal

47

What are three tricyclics antidepressants

Amytriptyline
Desipramine
Doxepin

48

What monoamine uptake blocker causes depression in adolescents

SSRI's

49

What are two monoamine uptake blockers (SSRI) used as antidepressants

Fluoxetine (Prozac)
Sertraline (Zoloft)

50

What are two NE or mixed transport blockers

Venalfaxine (effexor)
Duloxetine (cymbalta)

51

What medications are used as mood stabilizers for bipolar

Lithium
Antiepileptic agents:
Valproic acid
Carbamazepine
Latotrigine (lomotil)

52

What Bensodiazepinesdrugs are used for anxiety disorders

Bensodiazepines: allosteric modulators of GABA
-sedative
--diazepam (Valium)
--Alprazolam (Xanax)
-Hypnotic
--Lorazepam (Ativan)
--Triazolam (Halcion)

53

What barbiturates are used for anxiety, everyday stress

Bupropion (BuSpar)

54

What drug is used for severe acute anxiety-panic attack

SSRI's: Paxil
Antidepressant: Venlafaxin

55

What drug is used for phobic disorders

SSRI:Zoloft

56

What stimulants are used to treat ADHD/ADD

Amphetamines (adderrall)
Methylphenidate (Ritalin)

57

What minor stimulant is used to treat ADHD/ADD

Modafinil

58

What drugs can be used to treat autism

Atypical antipsychotics
SSRI

59

What drug can be used to treat bulimia

Fluoxetine
other antidepressants