Amiodarone Flashcards Preview

Yomata Drugs > Amiodarone > Flashcards

Flashcards in Amiodarone Deck (13):
1

Trade name

Cordarone

2

Class

Anti-dysrhythmic agent class III

3

Mechanism of Action

Prolongs duration of action potential and effective refractory period, noncompetitive alpha and beta adrenergic inhibition, increases PR and QT intervals, decreases sinus rate, decreases PVR

4

Indications

Ventricular Fibrillation, ventricular tachycardia, and rate control in pots with history of WPW, Atrial fibrillation.flutter, or PSVT

5

Contraindications

Do not administer with other drugs that prolong QT internal (procainamide) or Lidocaine; Administer 1/2 dose if lidocaine given PTA

6

Adverse Effects

Nausea, vomiting, bradycardia, hypotension, asystole

7

Incompatibilities/ Drug interactions

precipitates at certain concentrations when mixed at a Y site with Sodium Bicarbonate or Furosemide

8

Routes of Administration

IV IO

9

Onset of Action

Onset varies, Duration of 1/2 life can be as long as 40 days

10

Adult dose

300mg bolus in pulsless VT/VF
150mg over 10min (15mg/min)
Max dose not to exceed 2.2grams in 24hrs

11

Pediatric Dose

5mg/kg IV over 10min
Max dose 15 mg/kg

12

Special considerations

Watch for hypotension and bradycardia
May prolong QT interval; establish baseline QT prior to admin
Must be mixed in D5W

13

Protocols used

A-10 V-fib/V-tach
A-11 V-tach with a pulse stable
A-11a V-tach with a pulse unstable
A-12 PSVT
B-7 V-fib/V-tach
B-8 V-tach w/ Pulse