Ondansetron Flashcards Preview

Yomata Drugs > Ondansetron > Flashcards

Flashcards in Ondansetron Deck (12):
1

Trade name

Zofran

2

Class

Anti-emetic

3

Mechanism of Action

Prevents nausea, vomiting by blocking serotonin peripherally, centrally, and in the small intestine

4

Indications

Administered in an effort to reduce the nausea or vomiting complication associated with certain existing medical illness, injuries, or medication side effects (first drug of choice)

5

Contraindications/ Precautions

Known hypersensitivity to the medication; Hepatic disease

6

Adverse effects

Bronchospasm(rare). chest pain, tachycardia, hypotension, pain at injection site, extrapyramidal symptoms, seizures.

7

Routs of admint

SL,IM, IN, or IV/IO

8

Onset of action

Rapid onset peak of 15-30 min and duration of 4-8hrs. Onset of IM is rapid with peak of 40min and duration is unknown

9

Adult dose

4-8mg, slow IVP, SL,IN,or IM if no IV

10

Pediatric dose

0.1mg/kg slow IVP, SL IN if no IV

11

Special considerations

Give undiluted when administering IM or IV/IO
Administer IV/IO slowly over at lease 30 seconds (preferably over 2-5min)
Observe for prolonged QT intervals

12

Protocols used

A-17: Diabetic emergencies
B-3 Pediatric resuscitation
B-14; Pediatric diabetic emergencies
E-18: intranasal medication device
E-24: WMD