Promethazine Flashcards Preview

Yomata Drugs > Promethazine > Flashcards

Flashcards in Promethazine Deck (11):
1

Trade name

Phenergan

2

Class

Phenothiazine, anti-emetic, anti-histamine

3

Mechanism of action

Acts on blood vessels, Gi, respiratory system by competing with histamine for HI receptor site; blocks action of histamine; possesses sedative properties, anti-cholinergic, and anti-emetic activity, potentiates the narcotic effect

4

Indications

Nausea, vomiting, motion sickness, sedation, potentiation of analgesic effects of narcotics

5

Contraindications

Hypotension in volume deleted pts. Do not use in pots that have anticholinergic syndromes, children , than 3 yrs of age, hypersensitivity to phenothiazines phlebitis, pregnancy

6

Adverse effects

EPS, drowsiness, hypotension, palpitations

7

Routs of admin

IV/IO - must be diluted or IM if no IV

8

Onset of action

Onset 3-5 min peak at 30-60 min duration 4-6hrs

9

Adult dose

6.25 - 25mg IV/IO

10

Pediatric dose

Not

11

Protocols used

A-17: Nausea and Vomiting
B-3: Pediatric Nausea and Vomiting