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Flashcards in Cardene Deck (13):
1

Generic name

Nicardipine

2

Class

Calcium Channel Blocker

3

Mechanism of Action

Inhibits calcium ion influx across the cell membrane

4

Indications

Hypertension in subarachnoid bleeds, Hypertensive urgency/crisis

5

Contraindications

Advanced aortic stenosis; caution in heart failure or significant LV dysfunction because of the negative inotropic effect; caution in beta blocker usage

6

Adverse effects

Hypotension, headache, nausea, and vomiting, tachyarrhythmia

7

Incompatibilities/Drug interactions

Possible with fentanyl and vecuronium in same line

8

Routs of admin

IV drip. Do not push

9

Onset of action

1-2 minutes; peak 2-7 minutes; duration of effects is 44 minutes

10

Adult dose

2.5mg/hr - 15 mg/hr IV: titrate in increments of 2.5 mg/hr every 15 minutes

11

Pediatric dose

Not approved

12

Special Considerations

Most common side effect is rapid drop in blood pressure: avoid hypotension in possible stroke patient; Continuous monitor blood pressure, heart rate and EKG

May produce a prolonged duration of effect in renal and hepatic patients.

13

Protocols Used

A-16 Hypertension