Nitoglycerin Flashcards Preview

Yomata Drugs > Nitoglycerin > Flashcards

Flashcards in Nitoglycerin Deck (13):
1

Trade Name

Nitrostat, Nitro Spray, Tridil

2

Class

Vasodilator

3

Mechanism of action

Smooth muscle relaxant acting on vascular, uterine, bronchial, and intestinal smooth muscle,; reduces workload on the heart by causing blood pooling (depressed preload); arterial vasodilation 9 decreased after load); coronary artery vasodilation; increases blood flow to myocardium; decreases myocardial oxygen demand

4

Indications

Acute coronary syndromes, acute MI, congestive heart failure with edema

5

Contraindications

Hypovolemia, ICP, Bradycardia, SBP

6

Adverse effects

Hypotension reflex tachycardia, bradycardia, decreased coronary perfusion at high doses (secondary to hypotension), headache secondary to dilation of the meningeal vessels.

7

Incompatabilites/ Drug interactions

Other vasodilators; erectile dysfunction medications within the pst 48 hours

8

Routes of administration

IV, SL spray

9

Onset of Action

Onset in seconds peak of 5-10 min; duration of 15min

10

Adult dose

one full spray is 0.4mg may report x3 provided SBP.140mmHg
Nitro drip titrate to effect

11

Pediatric dose

Not indicated

12

Special considerations

Caution in use on patients who have never used NTG; hypotension more commonly seen in the elderly
Brady-dysrhythmias and hypotension usually respond to shock position and fluids
Caution in patients presenting with an acute inferior MI; RVMI may be present affecting filling pressures; administer fluid bolus prior to admin of nitrates

13

Protocols used

A-5: Chest pain
A-6: CHF
A-6b: CPAP