Anemia I Flashcards Preview

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Flashcards in Anemia I Deck (15):
1

proteins on membrane of RBC

spectrin
actin

2

increases RBC affinity for hemoglobin

decrease temp
decrease DPG
increase pH

3

decreases RBC affinity for HB

increase temp
increase DPG
decrease PH

4

two general ways to become anemic

decreased production
or increased destruction

5

MCV equation

%HCT x 10/RBC

6

MCH normal

27-34

7

MCHC normal

32-37

8

RDW normal

11.5-14.5

9

normal reticulocyte count

1%

10

increased RDW

ansiocytosis
increased variability in RBC size

11

polychromasa

indicates a shift in marrow reticulocytes nto the periphery in response to increase stimulation (aka increased epo)

12

you want to have increased reticulocytes when..

anemic
to show that your body is trying to compensate

13

reticulocyte production index

tells you if the bone marrow is adequately compensating for the degree of anemia

14

RPI equation

reticulocyte percentage x (HCT/normal HCT)/ maturation factor (days n marrow)

>2: adequate response
<2: inadequate response

15

maturation term def and normal

maturation time of RBCs in days at various levels of anemia

normal = 1