Flashcards in Intro to WBC Deck (18):
1
Absolute Neurtrophil Count
ANC= WBC x (%PMN + %bands)
2
leukocytosis
total WBC elevated above normal range
3
band news
immature neutrophil
4
patterns of leukocytosis/neutrophilia
shift neutrophila
left shift
leukemoid rxn
leukoerythroblastic rxn
leukemia
5
shift neutrophilia
demargination of marginal pool w/o proliferation
moderate in degree, rapid onset
6
shift neutrophilia generally seen with
steroids
epi injection
stress
seizures
7
left shift
more bands and occasional metamyelocyte in periphery
8
leukemoid rxn
demargination and marrow proliferation
--increase in both mature and immature forms-->
involves a left shift
9
leukemoid rxn seen w/
infection, inflammation, metastatic cancer, G-CSF
10
leukoerythroblastic rxn
seen w/ damaged bone marrow causing premature release of precursors cells
11
you may see this cell in a leukoerythroblastic rxn
tear drop cells
12
neutropenia
an absolute PMN count below normal range 2200-7000 cells/ul
13
congenital causes of neutropenia
cyclic neutropenia (autosomal dominant)
severe congenital neutropenia (auto dom)
kostmann syndrome (auto recessve)
14
acquired causes of neutropenia
infection
drug/toxin
nutritional deficiencies
neoplasm
hypersplenism/splenomegaly
immune-induced
15
ANC no significant risk for infection
1000-1500
16
ANC some increased risk, fever managed as outpatient
500-1000
17
ANC significantly increased risk of infection- cut off for antibiotics/hospitalization
<500
18