Pharm Randoms

Question 1

first line of care for diabetics with HTN

Answer 1

ace inhibitor

Question 2

4 times of sympatholytic agents

Answer 2

act within CNS
act on autonomic ganglia
act on post-ganglionic neurons
block peripheral adrenergic receptors

Question 3

what can clonidine help with

Answer 3

withdrawal symptoms of opioids

Question 4

trimethaphan will

Answer 4

almost never be used, maybe just by anesthesiologist when patient is knocked out

only given by IV

Question 5

1st drug approved for early BP lowering

Answer 5

reserpine

Question 6

B-blockers will not

Answer 6

reduce chance of having a stroke, but a pt with HRN and a fib- 1st line because two birds one stone

Question 7

labetolol is typically

Answer 7

not a first line drug due to so many side effects

Question 8

ace inhibitors help with

Answer 8

angioedema

Question 9

no B2 blockers for

Answer 9

asthma

Question 10

angina

Answer 10

propanolol

Question 11

goal BP reduction

Answer 11

25%

Question 12

best anti HTN drug for pregnancy

Answer 12

clonidine/methyldopa

**treat to avoid pre-eclampsia

Question 13

ACE inhibitors delay

Answer 13

development of renal failure

Question 14

positive chronotropic agent

Answer 14

increases HR via SA

Question 15

positive dromotropic agent

Answer 15

increase conduction in AV node mostly by S and PS

Question 16

remodeling response is also known as

Answer 16

proliferative response

Question 17

low preload

Answer 17

crystalloid

blood

Question 18

bradycardia

Answer 18

atropine
isoproterenol
pacemaker

Question 19

tachycardia

Answer 19

cadioversion

antiarrhythmic drugs

Question 20

dec contract

Answer 20

epi
dopamine
dobutamine
calcium
glucagon
digoxin

Question 21

excessive vasoconstriction

Answer 21

lisinopril
hydralazine
prazosin
carvedilol
nitroglycerin
nitropursside

Question 22

excessive or abnormal contractility

Answer 22

metoprolol

verapamil

Question 23

atropine sulfate avoid in

side effects

Answer 23

patients with glaucoma,

obstructive uropathy, gi obstruction, ileum, toxic megacolon

Question 24

hydralazine is not

Answer 24

useful by itseld

Question 25

aldosterone side effect

Answer 25

hyperkalemia

Question 26

how to prevent chronic remodeling

Answer 26

block effects of aldoserone on cardiac tissue (spirnolactone) block stimulation of myocardial beta-1 R SLOWLY/GENTLY block production of AT II or ARBs

Question 27

milk thistle

Answer 27

hepatoprotective by stimulating nucleolar polymerase A -->ribosomal protein synthesis

Question 28

glucosamine

Answer 28

inflammation osteoarthritis degeneration of cartilage glycosaminoglycans adverse- GI, headache, leg pain, edema, itching

Question 29

GIngko

Answer 29

memory and concentration improves tolerance of brain tissue to hypoxia by increasing cerebral blood flow

Question 30

ginseng

Answer 30

overall health, performance, stamina enhancer--immuno stimulation improves release of ash--CNS stim and inhib

Question 31

garlic

Answer 31

atherosclerosis, high cholesterol/LDL inhib HMG-COA reductase--increased fibrinolysis

Question 32

ginger

Answer 32

anti-emetic, treatment of nausea and committing, motion sickness interact with with 5ht R inhibit thromboxane

Question 33

Echinacea

Answer 33

treat prevent cold and flus activate phagosomes, tnf, etc

Question 34

St John's wort

Answer 34

depression, anxiety inhibit synaptosomal uptake of 5ht, da, and NE

Question 35

saw palmetto

Answer 35

benign prostatic hypertrophy, inhalammation reduce uptake of testosterone and DHT

Question 36

Soy

Answer 36

relief of symptoms and pre and post- menopause women interact with estogren R

Question 37

herb-drug interactions

Answer 37

cytochrome P450 enzymes UGTs P-gp

Question 38

cheese reaction

Answer 38

tyramine in cheese, metabolized by MAO, if taking MAO tyramine builds up and can potentiate sump CV activity by releasing NA-->HTN response

Question 39

TH2

Answer 39

associated with asthma

Question 40

cellular action B2 agonist

Answer 40

B2 agonist binds R-->GPCR-->increase camp-->protein kinase-->reduces ca2+-->relaxes smooth muscle

Question 41

3 other properties of B2 agonists

Answer 41

enhance mucociliary clearance decrease microvascular permeability suppress mediator release from inflame cells

Question 42

Gemfibrozil

Answer 42

elevates liver function tests, do not use with statin

Question 43

aspirin and plavix togehter

Answer 43

bruise everywhere

Question 44

NO

Answer 44

nitric oxide

Question 45

N2O

Answer 45

nitrous oxide

Question 46

NO2

Answer 46

nitrite

Question 47

NO2

Answer 47

nitrate

Question 48

antiarrhythmics

Answer 48

significantly prolong depolarization (QT interval) and therefore can result in tornado de pointe as a form of pro-arrhthmia

Question 49

only anti arrhythmic drug that proves mortality is

Answer 49

BETA BLOCKER

Question 50

what is the best thing to use fir an arrhythmia

Answer 50

ICD

Question 51

which class prolongs QT most

Answer 51

III and Ia

Question 52

What antiarr has been shown o reduce mortality post MI?

Answer 52

propanolol

Question 53

chronotropic agents

Answer 53

increase in HR via SA

Question 54

positive dromotrophic agents

Answer 54

increase in conduction in AV node mostly innervated by S and PS

Question 55

total cholesterol levels

Answer 55

desirable 240

Question 56

LDL levels

Answer 56

desirable 160

Question 57

HDL levels

Answer 57

desirable >50 borderline 40-50 bad <40

Question 58

never use these drugs

Answer 58

Beta antg cholinergic agonist adenosine aspirin and nsaids

Question 59

ace inhibitors and asthma

Answer 59

dry cough

Question 60

aminiosterioids

Answer 60

pancuronium veruronium rocuronium

Question 61

benzylisoquinolones

Answer 61

cistracurium | d-tubocranine

Question 62

Pancuronium

Answer 62

renal clearance

Question 63

vecuronium

Answer 63

hepatic clearance

Question 64

rocuronium

Answer 64

hepatic cleareance

Question 65

cisatracurium

Answer 65

inactivated by plasmaChE