ANS Flashcards Preview

Drug Reactions > ANS > Flashcards

Flashcards in ANS Deck (15):
0

Cholinomimetic Agents

(3)?

- Exacerbation of Asthma + COPD
- Peptic Ulcers
- Miosis + Cycloplasm

1

Anti-Cholinesterase (AchE) Poisoning

Causes, Pres ("DUMBBELSS: Epi + 9), RX (2)?

Organophosphates (ie in Insecticides) irreversibly inhibit AchE.

PRES: Farmers. * "DUMBBELSS" *
- Diarrhea
- Urination
- Miosis
- Bronchospasm
- Bradycardia
- Excitation of CNS & Skel muscle
- Lacrimation
- Sweating
- Salivation

RX: (Person is too cholinergic therefore we must make them
ANTI-cholinergic ->
give them Anti-Cholinergics = Muscarinic Antagonists)
- Atropine
- Pralidoxime

2

Atropine Toxicity

Pres (5), Comp (3, pop affected for each)?

"Hot as a hare, Dry as a bone, Red as a beet, Blind as a bat,
Mad as a hatter."

PRES:
-↑body temp (due to↓sweating)
- Dry skin & mouth, Urine retention & Constipation
- Flushed skin, Rapid pulse
- Cycloplegia
- Disorientation

COMP:
- Hyperthermia in infants
- Urine retention in men with BPH
- Acute Angle-Closure Glaucoma in elderly

3

a Agonists (Epi + Brimonidine)

(4)?

- Mydriasis
- Ocular hyperemia
- Blurry vision
- Allergic rxs + Pruritus

4

a1 Blockers / Antagonists

(2)?

- Orthostatic Hypotension (1st dose only)
- Headache + Dizziness

5

a2 Blockers / Antagonists (Mirtazapine)

(2)?

- Sedation (??)
-↑appetite +↑Cholesterol

6

b Agonists

HYPOkalemia

7

b Blockers / Antagonists

CI, (5)?

*** Use with caution in Diabetics (may mask signs of hypoglycemia) ***

- HYPERkalemia
- Impotence
- CV: Bradycardia, CHF, AV Block
- Exacerbation of Asthma
- CNS: Sedation + Sleep alterations

8

Cocaine

(2)?

- Coronary vasospasm
- Arrhythmias

9

Methyldopa

Direct-Coombs+ Hemolytic Anemia

10

Metoprolol

Dyslipidemia

11

Phenoxybenzamine

(2)?

- Orthostatic Hypotension
- Reflex Tachycardia

12

Drug Class that causes Mydriasis (pupil dilation)?

a-Agonists (Epi + Brimonidine)

*** Therefore CI in Closed-Angle Glaucoma ***

13

Drug Classes that cause Miosis (pupil constriction)?

(2)?

- Cholinomimetics
- Opioid Analgesics

14

Drug Class that causes Miosis (pupil constriction) +
Cyclospasm (ciliary muscle contraction)?

Cholinomimetics