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Flashcards in RENAL Deck (18):
0

Mannitol (1)

CI (2)?

Pulmonary Edema

CI:
- CHF
- Anuria

1

Diuretics (3)

- Dehydration
- Hypokalemia (except for K-sparing diuretics)
- Hepatic Encephalopathy (due to↓NH3 removal -> NH3 toxicity)

2

CA Inhibitors

RTA 2

3

Loop Diuretics (Furosemide + Ethacrynic acid)

(6: "OH DANG"), CI (2)?

* "OH DANG" *

O- Ototoxicity
H- Hypokalemia
D- Dehydration
A- Allergy (Sulfa)
N- Nephritis (Interstitial)
G- Gout (can cause hyperuricemia)

CI:
- NSAIDs (opposing effects on PGE -> no dilation of A.A -> Interstitial Nephritis)
- Gout patients

4

Thiazides

(5: 4 "HyperGLUC" + 1)?

- Hyperglycemia
- Hyperlipidemia
- Hyperuricemia
- Hypercalcemia

- Torsades de Pointes / Prolonged QT

5

Thiazides + Furosemide

Gout

6

K-Sparing Diuretics

RTA 4

7

ACE Inhibitors

(6: *THINK: "Captopril's CATCHH"*), CI (2)?

- Cough (due to↑Bradykinin)
- Angioedema
- Teratogen (-> fetal renal malformation)
- Creatinine (↓GFR)
- Hypotension
- Hyperkalemia

CI:
- C1-Esterase Inhibitor Def (Complement Def)
- Renal artery stenosis (b/c constrict efferent arterioles ->↓GFR -> renal failure in these patients)

8

Drug that causes Antiandrogen effects / Gynecomastia?

Spironolactone

9

Drugs that cause Diabetes Insipidus

(2)?

- Demeclocycline
- Lithium

10

Drug that causes Fanconi's Sx?

EXPIRED Tetracycline

11

Drugs that cause Hemorrhagic Cystitis

(2: "---famide")?

- Cyclophosphamide
- Ifosfamide

12

Drugs that cause Interstitial Nephritis

(3)?

- NSAIDs
- Furosemide
- Methicillin

12

Drugs that cause RTA Type 1

Amphotericin B toxicity

14

Drugs that cause SIADH

(2)?

- Carbamazepine
- Cyclophosphamide

15

Drugs that cause Renal TCC

Cyclophosphamide

16

NEPHROTOXIC Drugs (6)

General Pres (4),
Drugs (6: 1 Onc + 5 Antibiotics)?

PRES:
- Nephropathy
- Nephritis
- Hematuria
- Renal Failure

DRUGS:
- -platin

- Vancomycin
- Aminoglycosides
- Sulfonamides
- Amphotericin B
- ALL Antiviral 'Nucleic Acid Syn Inhibitors' EXCEPT Ribavarin

17

NEPHROTOXIC Substances (5)

- Ethylene Glycol
- Lead

- Myoglobin (ie Crush injuries to muscle)
- Urate (ie Tumor Lysis Sx)
- Radiocontrast Agents