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Flashcards in antifungals Deck (6)
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1

mechanism of amphotericin B

binds ergosterol and forms pores in membrane

2

mechanism of azoles

inhibits ergosterol synthesis by inhibiting fungal p450 that converts lanosterol to ergosterol

3

mechanism of flucytosine

inhibits DNA synthesis

used with amphotericin B

4

mechanism of nystatin

binds ergosterol and increases permeability of cell membrane

5

mechanism of Caspofungin

inhibits cell wall synthesis by inhibiting beta glucan

6

mechanism of griseofulvin

disrupts mitosis by interfering with microtubule formation.
fungal-static