Flashcards in Biochemistry- Amino Acids and Proteins Deck (64)
Tryptophan is a precursor for what neurotransmitter?
The reaction of tryptophan to serotonin requires what vitamin as a cofactor?
Tryptophan can also be turned into what molecule?
Phenylkeonturia is a genetic inability (lack of phenylalanine hydroxylase) to convert phenylalanine into what aminoacid?
Tyrosine is the precursor for which 2 neurotransmitters and what is the intermediate substance produced?
Norepi, and Epinephrine
What is the rate-limiting enzyme for the production of L-DOPA (and therefore catecholamines in general) from tyrosine?
What inhibits and promotes the activity of tyrosine hydroxylase?
Promotes: cold, stress
What vitamin is needed as a cofactor for the production of Norepi from dopamine?
What is the name of the enzyme that breakdown Norepi and epinephrine?
What is the breakdown product of MAOs action of norepi and epic?
vanillmandelic acid (VMA)
What are the 3 branched chain amino acids?
BCAAs: valine, isoleucine, leucine
Post-translational modification of proline and lycine to form hydroxylycine and hydroxyproline in collagen formation requires what vitamin?
Which are the only 3 amino acids that can be posttranvslationally modified by phosphorylation?
serine, threonine, tyrosine
Acetylcholine is formed from what amino acid?
GABA (gamma amino butyric acid) is formed from what amino acid?
Glutamate/ Glutamic acid
The reaction of glutamic acid to GABA requires what vitamin as a cofactor?
Histamine is formed from what amino acid?
Which amino acid is the main methyl donor in the body?
What are the 6 amino acids that can be catabolized by skeletal muscle?
What are the 3 amino acids that make up the tripeptide glutathione?
Cysteine, Glycine and glutamic acid
What are the 2 initial precursors for heme synthesis?
Glycine and succinyl CoA
What amino acid is the main transporter of nitrogen (ammonia) in the blood?
Alanine can be converted into what substance?
What amino acid is a major component of actin and myosin? What form does it take?
Histadine in the form of 3-methyl histadine
What type of bond holds together the amino sequence of peptides?
what are the only 2 sulphur containing amino acids?
What 2 bonds hold a secondary protein structure?
disulfide, weak covalent bonds
3D folding is seen is which level of protein structure?
2 or more single polypeptide chains bonded by weak bonds is called what?