Bioethics Flashcards
(14 cards)
1
Q
history of animal research
A
- dates back 3000+ years
- Renaissance
- cruelty of animals act (1876)
2
Q
animal research at UoN
A
- code of research conduct and research ethics
- animal research
- UK research integrity office: code of practise
- concordant to support research integrity
3
Q
general principles
A
- responsible use of animals as experimental subjects
- no other reasonable option
- medicine
4
Q
animal subject rules
A
- minimum number required to obtain valid use
- more than momentary or pain = anaesthesia = not important
- killed humanely if necessary
- well homed
5
Q
historical benefits of animal use
A
medical:
- combat pandemics
- anatomy
- cardiovascular and nervous systems
psychological
- learning and memory
- brain behaviour interactions
- social, attachment, development
- treatments
- transplants - 1954, 50,000
6
Q
humans in biological research
A
poor, blind, slaves, prisoners, the mentally ill
7
Q
human research at UoN
A
- WHO - declaration of Helsinki
- UKRIO - code of practise for research
- UK GDRR
human ppts - no long term damage
- reward needs to be worth any risk
- informed consent
8
Q
moving hurdles
A
updating guidelines
hurdles:
- research often uses animals
- before birth or early years
- long term consequences
9
Q
ethics in biological research
A
- ongoing process
- ethics continue to change
- dialogue
- transparent
10
Q
Neubaeur twins
A
- sealed until 60s
- separated at birth
- long term effects
11
Q
contemporary gynaecology
A
links back to experiment conducted on slaves
12
Q
Los Alamos Plutonium
A
- unknowingly injected with plutonium during GP appointments
- snatched Kelley’s body after radiation exposure without permission
13
Q
Tuskegee syphilis experiment
A
- infected with syphilis
- lied about treatment > placebo
- fuelled congress led legislation within USA
14
Q
HeLa cells
A
- unknowingly had immortal cells harvested and circulated
- regarded as historically wrong
