Blood disorders drugs Flashcards Preview

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Flashcards in Blood disorders drugs Deck (12):
1

Types of drugs for blood disorders

Anticoagulants
Thrombolytics (dissolves clots)
Anemia (RBCs lack iron, vitamin B12, or folic acid)

2

Anticoagulants

heparin
warfarin (Coumadin)
dalteparin
enoxaparin

3

heparin

Anticoagulant
Injection only
Monitored by PTT (partial thromboplastin time: intrinsic)
Antidote: protamine sulfate
Safe for pregnancy

4

Generic name: warfarin

Brand name: Coumadin
Anticoagulant
Tablet only
Monitored by PT (prothrombin time: extrinsic)
Interacts with antibiotics and NSAIDs
Not safe for pregnancy

5

Generic name: dalteparin

Brand name: Fragmin
Anticoagulant

6

Generic name: enoxaparin

Brand name: Lovenox

7

thrombolytics

Dissolve clots quickly
Interacts with anticoagulants, anti-platelet drugs, and NSAIDs -> Increased bleeding
streptokinase
urokinase
Anything that ends in -kinase

8

-kinase

dissolves clots quickly

9

anemia

Red blood cells are depleted of iron, vitamin B12, or folic acid

10

iron

travels on hemoglobin in the RBC (hemoglobin carries oxygen)
ex> ferrous sulfate (FeSO4) - Feosol
ferrous gluconate - Fergon
ferrous fismarate - Feostat iron
Concerns:
Must stay away from antacids, coffee, tea, milk
Interferes with TCN (tetracycline)
Take on empty stomach
Stains teeth: Liquid iron for children should be dissolved in juice.

11

Vitamin B-12 deficiency

= Cyanocobalamin deficiency (anemia)
Impaired DNA synthesis
Stunted maturity of RBC

12

Folic acid deficiency

= folate deficiency (anemia)
Impaired DNA synthesis
Stunted maturity of RBC