Bone and soft tissue Flashcards

(47 cards)

1
Q

What are the parts of the musculoskeletal system

A

Bone, skeletal muscle and connective tissue

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2
Q

What are the different types of connective tissues? In joints

A
  • Tendon
  • ligament
  • cartilage- structural support, protect tissues ans attachment sites
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3
Q

Compare number of bones of children and adult

A

Children- 270

adult- 206 (including sesamoids)

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4
Q

what are the fucntions of the skeletal system?

A
  • movement
  • support
  • protection of vital organs
  • calcium storage
  • haematopoeisis- bone marrow
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5
Q

what are the different classes of bones by shape and where can you find them?

A
  • Flate bone- frontal bone
  • short bone- carpal bones
  • irregular bone- vertebrae
  • sutured bone- skull
  • sesamoid bone- patella
  • long bone- femur, tibia, humerus
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6
Q

what is an osteogenic cell and its properties?

A

Bone stem cell

it makes osteoblasts

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7
Q

what is an osteoblast and what are its properties

A

made form osteogenic cell, it forms bone

secretes OSTEOID and catalyse mineralisation of osteoid

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8
Q

what is an osteocyte and what are it’s properties?

A

Mature bone cell

formed when an osteoblast becomes embede din its secretions

sense mechanical strain to direct osteoblast and osteoclast activity

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9
Q

what is an osteoclast and what afre it’s properties?

A

Bone breaking cells; helps in remodelling of the bone

dissolve and resorb bone by phagocytosis

derived from bone marrow

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10
Q

where can you find osteocytes?

A

embedded in the matrix (lacuna)

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11
Q

where can you find osteoblasts?

A

Growing portions of bone including periosteum and endosteum

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12
Q

where can you find osteogenic cells?

A

deep l,ayers of periosteum

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13
Q

where can you find osteoclasts?

A

Bone surfaces and at sites of old, injure dor unneeded bone

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14
Q

what are the components of the bone matrix? draw it

A

60% inorganic

40% organic

they all have sub component

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15
Q

what are the properties of immature bone

A
  • first bone made
  • replaced by mature bone
  • weak- as its laid out in woven manner
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16
Q

what are the types and subtypes of mature bone

A
  • It is mineralised woven bone
  • It has lamellar structure- relatively strong

types of mature are: cortical and cancellous

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17
Q

Contrast cortical and cancellous bone briefly.

A

cortical bone- compact dense bone; it is suitable for weaight bearing. heavy

Cancellous- Spongy bone; honeycomb structure. not suitable frow weight bearing

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18
Q

What are the components and organisation of the compact cortical bone

A

Lacunae surrounded by mineralised matrix- they all form part of the Osteon (HAVERSIAN system).

They are repeated over and over around a central HAVERSIAN canal

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19
Q

What does the HAVERSIAN canal contain

A

Blood vessels, nerves and lymphatics

20
Q

What is a Lacunae and Volkmanns canal

A

Lacunae- small spaces containing osteocytes. Tiny canaliculi radiate from lacunae filled with ECF

Volkmans canal- transverse perforating canals

21
Q

Label the structure of a long bone - draw

what is the most common location of a fracture and why

A

1) diagram
2) femur neck- connected to hip bone; most of the pressure from walking pass through it

22
Q

What occurs during intramembranous ossification ? I.e. what bone develops

A
  • Used to form flat bones of skull, clavicle and mandible
  • bone development from fibrous membrane
  • mesenchymal cell is used as a template
23
Q

Outline the steps of intramembranous ossification

A
  1. Mesenchymal cell scondense and turn to osteoBLAST- ossification centre forms
  2. osteocytes forms as osteoid traps osteoblasts
  3. Trabecular matric and periosteum forms
  4. compact bone develops superficially or cancellous bone. Bone marrow forms
24
Q

During endochondral ossification what bone develops and where does it start from?

A

Long bones develop from a hyaline cartilage model

25
Which takes longer? Intramembranous or endochondral ossification
Endochondral
26
What is the primary and secondary ossification centres for endochondral ossification
Primary- Diaphysis Secondary- Epiphysis
27
Outline the step by step model of endochondral ossification
1. **Bone collar formation** - causes by osteoblast forming bone on surfaces **around** it 2. **Cavitation** 3. **Periosteal bud invasion**- (containing blood vessesl, lymph etc) 4. **Diaphysis elongation** 5. **Epiphyseal ossification-** (long bones have 2, short have 1 and irregular have many secondary ossifcation centres). This occurs after birth. Articular cartilage made by chondrocytes at epiphsyeal plates.
28
Explain what happens during interstitial growth(long bone lengthening)
It occurs in the epiphyseal plate The epiphyseal side - hyaline cartilage active and dividing to form hyaline cartilage matrix diaphyseal side- cartilage calcifies, dies and replaced by bone
29
What is Appositional growth
When there's deposition of bone beneath the periosteum to increase thickness
30
Outline the steps of appositional growth
31
What are the functions and properties of tendons?
* Attaches skeletal muscle to bone * transmit muscle force to bone * made of collagen fibres arranged in bundles * stiff and strong
32
What is the microstructure of tendon ?
Made up of collagen (86%), 2% elastin, 1-5% proteoglycan and 0.2% inorganic (Mn, Cu) dry mass of 30% of total mass in water parallel arrays of collagen fibres closely packed together
33
What is the name of the connective tissue covering a tendon (lots of tertiary fibre bundles)
EPITENON
34
What are the features of ligaments
* Have subunits that tighten or loosen depending on joint position * NOT densely innervated or vascularised * contain some blood vessels and nerves in outer covering (epiligament) * contain proprioceptors * transmit pain signals via type C fibres
35
What does a normal ligament consist of?
* 90% Type 1 collagen * 9% Type 3 collagen- immature and in greater proportion in healing tissue * 1% fibroblast cells; they make collagen
36
What is the function of a cartilage
Acts as a shock absorber to reduce friction covers and protects long bones at joints
37
What cells are cartilage made out of? What di they produce
Chrondrocytes- make large collagenous ECM and ground substance
38
What are the 3 types of cartilages?
1. Elastic 2. Hyaline 3. Fibrocartilage
39
What are cartilages structural components of? what is the blood supply of cartilage
Ribs costal cartilages and IV discs Avascular
40
What are the 3 classification of joints ?
1. Fibrous- synarthoisis- doesnt move 2. Cartilaginous- Amphiarthrosis; moves limited 3. Synvovial- Diarthrosis- moves freely
41
What are the different types of synovial joints and where can you find them?
Pivot- Atlanto-Axial joint Hinge joint- elbow joint and knee saddle - between trapezium and 1st metacarpal Plane joint- between tarsal bones Condyloid- between radius and carpal ball and sock- hip joint; glenohumeral joint
42
What is the most common joint and protein in body?
Joint- synovial protein- collagen
43
What are the component of a synovial joint capsule
1. Articular capsule(outer)- keeps bone together structurally 2. synovial membrane- contains synovial fluid
44
What is the purpose of synovial fluid?
Lubrication- reduce friction nutrition shock absorption
45
What are the factors affecting joint stability?
* Joint shape * Ligament * tendons * cartilage(e.g.Glenoid labrum)
46
What are difference between shoulder and hip stability and their components
47
Why are dancers more prone to ligamentius injury ?
Flexible hence ligament is extra laxed and its overused hypermobility which increases injury risk.