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Flashcards in Cancer Theraputic Options Deck (18)
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1

What are the two main types of therapeutic option for cancer?

- prevention

- treatment

2

What are the different types of prevention therapeutic options?

- diet
- screening
- genetics
- medication

3

How is medication used in preventative therapeutic options of cancer?

Chemoprevention:

- primary (oesophageal/breast)
- secondary (previous H&N and lung)

4

What are the different types of treatment for cancer?

- local therapy

- systemic therapy

5

What are examples of local cancer therapy?

- surgery
- radiotherapy

6

What are examples of systemic cancer therapy?

- immunotherapy
- chemotherapy
- hormonal therapy

7

What are the 5 R's of radiography?

Radiosensitivity
Repair
Re-population
Re-oxygenation
Re-assortment

8

What is radiosensitivity?

How sensitive the cancer is to treatment

9

What is repair?

How well the cancer repairs itself (not used clinically due to HR issues)

10

What is re-population?

Does the cancer grow during treatment?

11

What is re-oxygenation?

A tumour with high penetration by oxygen responds more effectively to treatment

12

What is re-assortment?

Which part of the cell cycle is treatment carried out during?

Resting (G1) = not sensitive
Mitosis (M) = vary sensitive

13

What is adjuvant chemotherapy?

- to improve statistical survival of the entire population
- following surgery

14

What is neoadjuvant chemotherapy?

- to improve survival and reduce morbidity
- before surgery to allow its possibility

15

What are the main methods of immunotherapy?

- monoclonal antibodies

- programmed cell death pathway (PD-1)

- chimeric antigen receptor (CAR) T-cells

16

What are monoclonal antibodies?

synthesised antibodies that cannot be made in nature

17

What is the programmed cell death pathway?

- taking away the cancer's ability to hide
- used in melanoma treatment

18

What is the CAR T-cell mechanism of immunotherapy?

giving T-cells something they can recognise on the cancer