Flashcards in Cancer Theraputic Options Deck (18)
What are the two main types of therapeutic option for cancer?
What are the different types of prevention therapeutic options?
How is medication used in preventative therapeutic options of cancer?
- primary (oesophageal/breast)
- secondary (previous H&N and lung)
What are the different types of treatment for cancer?
- local therapy
- systemic therapy
What are examples of local cancer therapy?
What are examples of systemic cancer therapy?
- hormonal therapy
What are the 5 R's of radiography?
What is radiosensitivity?
How sensitive the cancer is to treatment
What is repair?
How well the cancer repairs itself (not used clinically due to HR issues)
What is re-population?
Does the cancer grow during treatment?
What is re-oxygenation?
A tumour with high penetration by oxygen responds more effectively to treatment
What is re-assortment?
Which part of the cell cycle is treatment carried out during?
Resting (G1) = not sensitive
Mitosis (M) = vary sensitive
What is adjuvant chemotherapy?
- to improve statistical survival of the entire population
- following surgery
What is neoadjuvant chemotherapy?
- to improve survival and reduce morbidity
- before surgery to allow its possibility
What are the main methods of immunotherapy?
- monoclonal antibodies
- programmed cell death pathway (PD-1)
- chimeric antigen receptor (CAR) T-cells
What are monoclonal antibodies?
synthesised antibodies that cannot be made in nature
What is the programmed cell death pathway?
- taking away the cancer's ability to hide
- used in melanoma treatment