Pathogens Flashcards Preview

Principles of Disease HQ > Pathogens > Flashcards

Flashcards in Pathogens Deck (11)
Loading flashcards...
1

Differentiate a pathogen from a commensal

Pathogen - a disease-causing organism
Commensal - an organism that's part of the normal flora of the body

2

What is meant by the pathogenicity of a pathogen?

It's capacity to cause infection

3

What two factors dictate pathogenicity?

Infectivity
Virulence

4

What two factors dictate infectivity?

Attachment
Acid resistance

5

What is infectivity?

Ability of a pathogen to become established

6

What is virulence?

Ability of a pathogen to cause harm once established

7

What three factors dictate virulence?

Invasiveness
Toxicity
Immune evasion

8

Name the three classes of pathogenic toxin

Exotoxin
Enterotoxin
Endotoxin

9

What is an exotoxin?

Released extracellulary (e.g. tetanus)

10

What is an enterotoxin?

An endotoxin that acts on the GI tract (e.g. cholera)

11

What is an endotoxin?

Part of the cell wall of a Gram negative bacteria (the lipopolysaccharide)