Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Histology > Cartilage > Flashcards

Cartilage Flashcards

(51 cards)

Start Studying
1
Q

3 functions of cartilage

A

Support

Cushion

Template for mature bone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Mature cartilage is (3)

A

Avascular

Aneural

Alymphatic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

How does cartilage receive nourishment if its avascular?

A

Blood vessels of surrounding CT (pericondrium= hyaline and elastic cartilage)

Synovial fluid within joint capsule (without pericondrium=fibrocartilage)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is the relationship between cartilage thickness and nutrients/oxygen?

A

Nutrients and oxygen must diffuse through the water of hydration within ECM which limits thickness of cartilage.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Acellular components of cartilage

A

ECM

  • ->Water
  • ->Ground substance
  • ->Fibers
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Components of ground substance and fibers in ECM

A

Ground substance

  • aggrecans
  • hyaluronic acid
  • GAG
  • Proteoglycans

Fibers

  • Collagen
  • Elastic
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Cellular components of cartilage (3)

A

Chondrogenic cells

Chondroblasts

Chondrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Immature cells that secrete ECM in cartilage

A

chondroblasts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Mature cells that are enveloped by the ECM into lacunae

A

Chondrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Types of growth in cartilage (2)

A

Appositional growth

Interstitial growth

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Perichondrium consists of 2 layers

A
  • Outer fibrous layer

- Inner cellular layer

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Outer fibrous layer of perichondrium made of

A

Type I collagen

Fibroblasts

Blood vessels

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Inner cellular layer of perichondrium made of

A

chondrogenic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Chondrogenic cells differentiate into (which do what)?

A

Chondroblasts which make ECM and become chondrocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

T/F Interstitial growth contains perichondrium

A

F

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

In interstitial growth, as cells make ECM

A

They move away from one another

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Where does interstitial growth occur

A

Articular cartilage (lacks perichondrium) and epiphyseal plates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

T/F Interstitial growth has chondrenic cell layer

A

F

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What are isogenous groups

A

In cartilage

Pairings of chondrocytes in lacunae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Territorial matrix

A

Immediately surrounding chondrocyte (more basophilic than interterritorial matrix)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Territorial matrix is poor in? Rich in?

Study These Flashcards
A

Poor-collagen

rich-proteoglycans (chondroitin sulfate)

22
Q

Interterritorial matrix

Study These Flashcards
A

Area outside of territorial matrix (less basophilic that territorial matrix)

23
Q

Interterritorial matrix rich in? poor in?

Study These Flashcards
A

Rich-type II collagen

Poor-Proteoglycans (chondroitin sulfate)

24
Q

3 types of cartilage

Study These Flashcards
A

Hyaline cartilage

Elastic cartilage

Fibrocartilage

25
Places hylaine cartilage is
Nose Tracheal rings larynx cartilage part of ribs bronchi articular surfaces
26
Color of hyaline cartilage
Blue/gray and translucent
27
Major component of hyaline cartilage
Type II collagen
28
Hyaline cartilage is important in
Endochondral ossification of long bones
29
Special form of hyaline cartilage
``` Articular cartilage (joint surfaces) Not covered by perichondrium ```
30
Elastic cartilage phenotype
Yellow and opaque
31
Where is yellow cartilage found
ear pinnae external and internal auditory tubes parts of larynx
32
High concentration of what in elastic cartilage
Elastic cartilage with type II collagen
33
What has more chondrocytes, elastic cartilage or hyaline cartilage
Elastic cartilage
34
Where is fibrocartilage found
Connections of tendons to bone Intervertebral discs Pubic symphsis Menisci of femorotibiial joint Meniscus of TMJ
35
T/F Fibrocartilage includes perichondrium
F
36
What's found in fibrocartilage
Large bundles of Type I collagen
37
Fibrocartilage resists
Compression and shear forces
38
Patters seen in fibrocartilage
Herringbone pattern Chondrocytes in rows of isogenic groups
39
Cartilage repair (with perichondrium) in young
Perichondrium still active and ensures supply of mesenchymal cells Interstitial and appositional growth activity present
40
Cartilage repair (with perichondrum in adult)
Perichondrium not active=regenerative activity decreased\ Loss of interstitial and appositional growth Repair by laying down granulation tissue which can turn into fibrocartilage (scar tissue)
41
Cartilage repair (without perichondrium)-Fibrocartilage
repairs poorly
42
Cartilage repair (without perichondrium)-Articular cartilage
Superificial-compensatory secretion by chondrocytes (pseudointerstial growth) Full thickness-when damage to subchondral bone...stem cells differentiate into fibrous CT, fibrocartilage, or bone
43
Chondrogenic cell physical traits - shape - nucleus - organelles - mito - ribosomes
Spindle shaped Ovoid nucleus Small Golgi appartus Few mitochondria Lots of free ribosomes
44
Chondrogenic cells differentiate into (2)
Chondroblasts or osteoprogenitor cells
45
Chondroblasts are derived from (2)
Mesenchymal cells within center of chondrification OR Chondrogenic cells of inner layer of perichondrium
46
Chondroblast physical traits - Organelles - Mito
Lots of RER Well developed Golgi apparatus Lots of mito Lots of secretory vessels
47
T/F chondroblasts help with interstitial growth
T
48
Chondrocyte physical appearance Young -Oraganelles -Mito Old - Organelles - Ribosomes
Young lots RER well developed Golgi apparatus lots of mito Old Lower amounts of organelles Lots of free ribosomes
49
Chondrocytes and lacunae | -Dehydration
Chondrocytes are in lacunaes If cell becomes dehydrated, cell pulls away from lacunae White space, is lacunae ("shell":
50
Lavender haze surrounding chondrocyte nucles
cytoplasm
51
Purpose of articular cartilage
Cushion

Histology (14 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions