Epithelium Flashcards

(68 cards)

1
Q

Basic functional unit of the body

A

cell

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2
Q

A collection of cells and material between cells that perform specialized functions

A

tissue

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3
Q

A structure or mass formed by basic tissues to perform specialized functions

A

organ

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4
Q

A group of organs that work together to perform specialized functions

A

system

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5
Q

Epithelium traits (2)

A

Covering and lining of surface

Secretion

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6
Q

Epithelium is derived from

A

ALL GERM LAYERS
Ectoderm
Mesoderm
Endoderm

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7
Q

Functions of epithelium (7)

A
  • protection
  • Transcellular transport (active and passive)
  • Secretion
  • Absorbtion
  • Selective permeability
  • Sensory detection
  • Contraction (myoepithelial cells)
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8
Q

Characteristics of epithelium (3)

A
  • Composed entirely of cells
  • Avascular (no blood vessels)
  • Polarity (apical, lateral, basal)
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9
Q

Physical arrangement of epithelium (3)

A

1-sheets of tightly bound cells (membrane)
2-Glands (single or group secretory)
3-Non-secretory individiul or small clusters of cells

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10
Q

Membrane epithelium arranged:

A

In sheets to cover body surfaces (inside and outside)

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11
Q

3 criteria for epithelial classification

A

1-Number of layers of cells
2-Shape of cells in surface layer
3-Special modification of epithelial cells

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12
Q

Number of layers of cells can be

A

Simple (1 layer of cells)

Stratified (more than 1 layers of cells)

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13
Q

Shape of cells in surface layer

A

Squamous-flat

Cuboidal-square

Columnar-rectangular

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14
Q

Classes of epithelium in sheets with unique characteristics

A

Transitional epithelium

Pesudostratified columnar epithelium

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15
Q

3 specialized modifications of epithelial cells

A

1-Apical cell membrane
2-Basal cell membrane
3-Cytoplasm

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16
Q

Special modification of epithelial cell

Apical cell membrane (3)

A
  • Kinocilia=long, mobile projections-CILIA
  • Microvilli=short projections-BRUSH BORDER
  • Stereocilia=long, non-mobile projections
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17
Q

Special modification of epithelial cell

Basal cell membrane

A

Basal infoldings=invagination in basal cell membrane

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18
Q

Special modification of epithelial cell

cytoplasm

A

Keratinization=deposition of proteinaceous filaments

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19
Q

Psuedostratified columnar epithelium

A
  • simple epithelium
  • Variable cell shapes
  • All cells attach to basement membrane
  • Not all cells reach surface of epithelium
  • Common with apical surface modification (cilia or sterocilia)
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20
Q

Transitional epithelium

A
  • stratified epithelium
  • shape of surface cells variable
  • Can stretch without breaking cell to cell attachment
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21
Q

Apical, basal, lateral polarity arrangement

A

Apical- toward lumen if present
Basal-attached to basement membrane
Lateral- on sides of cell that aren’t basal or apical

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22
Q

Adhesion of epithelial cells to other things via

A

Junctional complexes or terminal bars

on apical surface of cell

Glycocalyx and microvilli help

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23
Q

Types of attachments between epithelial cells (4)

A

Macula-spot
Zonula-girdle or belt
Occludens-tight seal
Adherens-site of adhesion

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24
Q

Desmosome is example of what type of attachement

A

Macula adherens

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25
Some specialized structures in junctional complexes (2)
Gap juntinos Hemidesmosomes
26
Intercellular bridges
desmosomes
27
Components of basement membrane (2)
1-Basal lamina | 2-Lamina relicularis or Lamina fibrorecticularis
28
Basal lamina
Made by epithelial cells - ->lamina lucida - ->lamina densa
29
Lamina relicularis or lamina fibroreticularis is made by
fibroblasts
30
Functions of the basement membrane (3)
- Attachment of epithelium - Filteration - Direct cell migration during wound healing
31
Definition of gland
One or more specialized cells that elaborate secretory products (material not related to their ordinary metabolic needs)
32
Glands originate from
Epithelial cells
33
Glands are formed by
Projections of epithelium at a surface of the body into underlying mesoderm (primitive CT)
34
Components of glands (2)
Parenchyma Stroma
35
Parenchyma of glands
Secretory epithelial cells Epithelial cells of ducts
36
Stroma of glands
CT matrix and cells Blood vessels Nerves
37
To be a gland: 6 criteria
1-presence or absense of a duct 2-Number of secretory cells (exocrine or endocrine) 3-Nature of secretory product of exocrine 4-Mode of release (secretion) of secretory product by cells of exocrine glands 5-Collective shape of groups of secretory cells of exocrine gland 6-Distance endocrine secretory product must travel
38
Gland with a duct
Exocrine gland: ducts transport secretory product to surface
39
Gland without duct
Endocrine gland:releases secretory product into blood vessels or tissue fluid for transport carried to other locations in the body
40
Example of unicellular gland
Goblet cell and APUD cell
41
Example of multicellular gland
Salivary gland and parathyroid gland
42
Nature of secretory product of exocrine gland (4)
- Serous secretion - Mucous secretion - Mixed secretion - Sebaceous secretion
43
Serous secretion product
Watery, rich protein
44
Mucous secretion product
Viscous, slippery, rich in sugar
45
Mixed secretion product
Components of serous and mucuos secretions
46
Sebaceous secretion product
Lipids (oily secretion termed sebum)
47
Mode of secretion of secretory product by exocrine gland (3)
- merocrine - apocrine - holocrine
48
Merocrine secretion
Secretory product released from secretory granule with NO loss of cytoplasm
49
Apocrine secretion
Small portion of apical cytoplasm pinched off and released with secretory product
50
Holocrine secretion
Entire cell released with secretory product
51
Collective shape of groups of secretory cells of exocrine gland (3)
Tubular (like test tube) Acinar (berry shaped with tiny lumen) Aleveolar (big berry with big lumen)
52
Distance secretory product of endocrine gland can travel (3)
- Autocrine - Paracrine - Endocrine
53
Autocrine
Endocrine glands use this Secretory product directly acts on same cell
54
Paracrine
Endocrine glands use this Secretory products acts on adjacent cells
55
Endocrine
Endocrine glands use this Secretory product travels via vasculature to act on distant cells.
56
Exocrine glands can be classified as (2) depending on duct
- Simple-duct is unbranced | - Compound-if duct does branch
57
Lobe vs lobule
Lobules are separated by septums (CT wall) WITHIN the lobe. Lobules hold individual secretory acini.
58
What's commonly found in the infoldings of basal cell membranes?
Elongated mitochondria to allow E to be used in active membrane transport system.
59
What will you find on epithelium that is exposed to extensive frction
Keratin. For protection
60
Classification of epithelium is based on
Morphology (cell layer, shape, special modifications)
61
Name of epithelium is based on
Specific site in the body
62
SSE that lines blood vessels, lymphatic vessels, and heart is
endothelium
63
Glyococalyx
Protective layer of glycoproteins
64
Goblet cells - Secrete - derived
Single cell gland - secrete mucus-->mucinogen (unhydrated precursor of mucus) - derived from endoderm
65
What composes junctional complex
tight junctions (zonular occludens) zonular adherens desmosomes (macula adherens) gap junctions (nexus)
66
Where can you see mitosis?
Basement membrane
67
Keratohyalin
Small basophilic granules in cytosplasm that are associated with aggregation of keratin filaments.
68
Transtional epithelum appearance is due to
Stretching