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CLS 304 > Cerebrospinal Fluid > Flashcards

Cerebrospinal Fluid Flashcards

(54 cards)

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1
Q

what color is CSF

A

colorless

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2
Q

where is CSF produced

A

the 4 ventricles of the brain

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3
Q

what secretes CFS

A

choroid plexus

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4
Q

function of CSF

A
  • supplies nutrient to nervous tissue
  • removes metabolic waste
  • cushions brain and spinal cord
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5
Q

what does the central nervous system consist of

A

brain

spinal cord

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6
Q

what is the outer layer of the central nervous system

A

dura mater

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7
Q

what is the middle layer of the central nervous system

A

arachnoid mater

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8
Q

what is the inner layer of the central nervous system

A

pia mater

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9
Q

what layers do CSF flow through

A

arachnoid mater and Pia mater

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10
Q

what are the protective coverings of the brain

A

bone
meninges
fluid

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11
Q

def? dura mater, arachnoid mater, pia mater

A

meninges

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12
Q

how is CSF made

A

hydrostatic pressure and active secretion

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13
Q

how many mL of CSF do adults have

A

85-150 mL

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14
Q

how many mL of CSF do neonates have

A

10-60 mL

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15
Q

what blood-brain barrier condition is blockage of drainage of CSF

A

hydrocephalus

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16
Q

treatment of hydrocephalus

A

sugary

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17
Q

how many tubes are used for CSF collection

A

3

sometimes 4

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18
Q

what kind of testing is prioritized if there is only a little bit of CSF

A

micro and cellular testing

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19
Q

if there is even blood distribution in all 3 tubes of CSF what does that indicate

A

hemorrhage

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20
Q

if there is uneven blood distribution in the 3 tubes of CSF what does that indicate

A

traumatic tap

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21
Q

true or false: CSF testing is not STAT

A

F

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22
Q

cause of xanthochromic (pink to orange) CSF sample

Study These Flashcards
A

bilirubin

breakdown of hemoglobin

23
Q

cause of clotted CSF sample

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A

protein

fibrinogen

24
Q

cause of pellicle (thick mmb/film) CSF sample

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A

protein

clotting factors

25
what method is used to count CSF cells
Neubauer hemocytometer counting chamber
26
how many WBC is normal per microliter in CSF sample
0-5
27
what are the most common WBCs seen in CSF fluid
lymphocytes and monocytes
28
normal ratio of lymphocytes to monocytes in CSF (adults)
70:30
29
def? increased amounts of normal cells
pleocytosis
30
pleocytosis helps determining the cause of what
meningitis
31
if you see lots of neutrophils in CSF what kind of meningitis is this
bacterial
32
``` if you see lots of lymphocytes in CSF what kind of ___ viral tubercular fungal parasitic syphilis is this ```
meningitis
33
if blast forms in CSF what is the clinical significance
acute leukemia
34
if lymphoma cells are in CSF what is the clinical significance
disseminated lymphomas
35
if plasma cells are in CSF what is the clinical significance
multiple sclerosis
36
if eosinophils are in CSF what is the clinical significance
parasites, allergic
37
if ependymal choroidal and spindle-shaped cells are in CSF what is the clinical significance
diagnostic procedures
38
if malignant cells are in CSF what is the clinical significance
metastatic carcinomas
39
what do neutrophil often contain in CSF
phagocytized bacteria
40
who is more likely to have a traumatic tap
children
41
in a traumatic tap how many WBC are there for every 1000 RBC
1 to 2
42
what do arachnoid, ependymal, and choroid plexus cells mistaken for
malignant cells
43
what stain is used for bacteria and fungi
gram stain
44
what stain is used for cryptococcus neoformans
india ink
45
what stain is used for tuberculosis meningitis
acid-fast stain
46
what stain is used for ameba naegleria fowleri
wright stain
47
normal amount of protein in CSF
15-45 mg/dL
48
what protein is monitored for multiple sclerosis
myelin basic protein
49
formula for CSF/serum albumin index
albumin CSF (mg/dL)/ albumin serum (g/dL)
50
what is the normal amount of CSF/serum albumin index
less than 9
51
in protein electrophoresis what is the 2nd band
tau protein
52
what kind of salt increases in both bacterial, fungal, or tuberculous infections
lactate
53
what a.a increases when ammonia levels increase
glutamine
54
what a.a is associated with loss of consciencness, coma, or liver disorders
glutamine

CLS 304 (21 decks)

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