Chapter 191 :: Antiviral Drugs

Question 1

treatments for herpes viral infections are most effective when initiated as early as possible, within 24 hours for varicella and 72 hours for herpes zoster onset

Answer 1

Acyclovir

Question 2

acyclovir crosses the human placenta and is excreted in breastmilk

safe for use

recommended for herpes treatment during pregnancy

Answer 2

so long as the nursing mother does not have active lesions near or on the breast

Question 3

does not require phosphorylation and is therefore active against many strains of virus that are resistant to acyclovir, famciclovir, or ganciclovir as a result of absent or reduced kinase activity.

Answer 3

Foscarnet