Chapter 52 :: Pemphigus Flashcards
1
Q
Two major types
A
pemphigus vulgaris and pemphigus foliaceus.
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2
Q
suprabasal acantholysis.
A
Pemphigus vulgaris
3
Q
subcorneal acantholysis.
A
Pemphigus foliaceus
4
Q
Desmoglein 1 & 3
A
Pemphigus vulgaris
5
Q
Desmoglein 1
A
Pemphigus foliaceous
6
Q
erosions can be induced in normal-appearing skin distant from active lesions by pressure or mechanical shear force
A
Nikolsky sign
7
Q
Essentially all patients with active PV or PF have a positive finding on a direct immunofluorescence study, which tests for IgG bound to the cell surface of keratinocytes in perilesional skin
A
Direct Immunofluorescence
8
Q
reported as a semiquantitative titer (indicating the last dilution at which the serum demonstrates a positive cell surface staining pattern)
A
Indirect Immunofluorescence
