Chapter 5 :: Growth and Differentiation of the Epidermis Flashcards

1
Q

Basal cells

A

Most often marked by the expression of keratins 5 and 14

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2
Q

Desmosomes

A

Cell-cell adhesions

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3
Q

Spinous cells

A

Basal to spinous differentiation is a highly regulated transition

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4
Q

Last function of granular cells

A

To die

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5
Q

Cornified envelopes

A

Products of terminal differentiation in the epidermis

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6
Q

The core consists of keratins surrounded by highly crosslinked networks of proteins, especially

A

Loricrin

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7
Q

The cross-linking is largely contributed by

A

Transglutaminases

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8
Q

Stratum corneum

A

Outside-in barrier

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9
Q

Tight junctions

A

Inside-out barrier and thus collaborate to form an effective barrier to the external environment

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