Chemistry 8 (Pregnancy) Flashcards

(45 cards)

1
Q

bilirubin peak absorbance

A

450nm

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2
Q

liley chart

A

deltaOD450 by gestational age

if in zone 3 or increasing in zone 2; then deliver if >36wk or transfuse if less

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3
Q

alpha subunit of hCG same as

A

TSh, FSH, LH

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4
Q

hCG first detectable at _____day, _____mIU/mL

A

6-8d

10-50mIU/mL

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5
Q

hCG level doubles every ____ days until level of ____ around ____

A

2days
1200
10weeks

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6
Q

between ____ and ____ level, hCG doubles every ____days

A

1200-6000

3days

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7
Q

hCG doubles every ____ days above____ until a peak of ____ around ____

A

4days
6000
100,000
end of first trimester

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8
Q

increased hCG in

A
multiples
polyhydraminios
eclampsia
HDFN
GTF
Tri21
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9
Q

abnormal pregnancy if hCH does not rise at least ___ in ___ or if it falls in that time

A

66% in 48hr

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10
Q

with transabdominal US, gestational sac detectable if hCG

A

6000

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11
Q

with transvaginal US, gestational sac detectable if hGC

A

1400

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12
Q

serum progesterone ____ assures IUP

levels ____ predictive of abnormal

A

> 25

<5

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13
Q

risk for malignant dz in partial and complete mole

A

<5%

20%

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14
Q

follow-up of mole

A

monitor weekly until undetactable x3wk, then monthly x1yr

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15
Q

Triple screen

A

hCG, AFP and estriol at 18wk

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16
Q

Quad test

A

triple screen plus dimeric inhibin A (DIA)

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17
Q

Advantage of DIA in quad test

A

stable during 2nd trimester

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18
Q

in diabeteic mothers, ___ and ___ are ___

A

uE and hCG mildly decreased

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19
Q

in smokers, ___ is increased and ___ is decreased

A

AFP increased

uE and hCG decreased

20
Q

pattern in tri18

A

decreased AFP, hCG and uE

21
Q

pattern in NTD

A

increased AFP
normal hCG
decreased uE

22
Q

pattern in Tri21

A

decreased AFP and uE

increased hCG and DIA

23
Q

increased AFP in

A
NTD
ophalocele
renal abnormalities
sacrococcygeal teratoma
cystic hygroma
hydrops
Turner
bowel obstruction
Twins
fetal demise
fetal-maternal hemorrhage
24
Q

uE is good indicator of

A

Tri18
Smith-Lemli-Opitz
hereditary deficiency of steroid sulfatase

25
DIA increased in
Trisomy 21
26
___ of fetal fibronectin has high ____ for preterm birth
absence | NPV
27
majority of lecithin produced by type II pneumocytes is
DSPC
28
test for getal lung maturity best to use if specimen is suboptimal
PG test
29
L/S ratio considered mature at
2:1
30
problems in L/S ratio
not reliable in DM meconium causes false low blood makes it be around 1.5
31
which tests not interfered by blood or meconium
PG and DSPC
32
foam stability index of ___ is considered mature
2:1
33
lamellar body number density of ____ is predictive fo maturity
>50,000
34
fluorescence polarization value of ____ is considered mature
290 immature)
35
influence of blood on fluorescence polarization
decreases high values, increases low values | if <230, definitely mature even with blood contam
36
values that increase in pregnancy
fatty acids triglycerides transport proteins GFR
37
cause of insulin resistance in preg
hPL
38
autoimmune dzs that tend to get better in preg
Graves | RA
39
autoimmune dzs exacerbated in preg
SLE
40
autoimmine dzs notorious for postpartum exacerbation
Graves | MG
41
Mortality in SLE during pregnancy due to
pulmonary hemorrhage | stroke
42
congenital heart block
assd with anti-SS-A or B in SLE
43
transient hyperthyroidism of hyperemesis gravidarum due to
very high hCG
44
labs in intrahepatic cholestasis
alk phos inreased 5-10x increased GGT and 5'-nucleotidase bile acids increased 10x increased conjugated bili
45
infections indicated in recurrent preg loss
Ureaplasma urealyticum | Chlamydia trachomatis