TM 5 (blood groups) Flashcards by Casey Gooden

Q

Rh null

A

stomatocytes, hemolytic anemia

altered S,s,U

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Q

f antigen

A

little e and little c together (r or R0)

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Q

great complement fixer with lots of dosage effect

A

Kidd

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Q

Most famous for delayed hemolytic transfusion rxn

A

Kidd

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Q

Glycophorin A carries

A

M, N antigens

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Q

Glycophorin B carries

A

S,s,U antigens

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Q

if S- and s-, may also be

A

U neg (2% AA)

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Q

clinically significant abs in MNS system

A

S,s,U

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Q

“N-like” antigen

A

terminal end of glycophorin B chain

only S-, s-, U- will make anti-N (also make anti-U)

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Q

what is most common Duffy phenotype in AA

A

Fy(a-b-)

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Q

Fya is more common in

A

Asians

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Q

Duffy in caucasians

A

Fya > Fyb

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Q

Fy(a-b-) protects against

A

P.vivax

P.knowlesi

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Q

Kell frequencies

A

K+ 9% of caucasian, 2% of AA

k+ almost everyone

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Q

as kell decreases, Kx ____

A

increases

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Q

Lacking Kx

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A

McLoud phenotype

decreased Kell Ags

Q

Kell system antigens are destroyed by

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A

thiol reagents

Q

Most common antibody after anti-D

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A

anti-K

Q

Kell hemolytic transfusion rxns

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A

extravascular

severe HDFN

Q

Kell null (K0)

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A

absense of all Kell Ags
Kx increased
makes anti-Ku

Q

ABs to Lutheran

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A

uncommon and insignificant

Q

Facts about Sda

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A

agglutinated by Dollichos biflorus

neutralized by guinea pig urine

Q

Usually insignificant HTLAs

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A

Chido, Rogers, Sda, Bg, Csa, York
insignificant
neutralized by serum

Q

Sometimes significant HTLAs

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A

Cartwright, Holley, Gregory

FyA antigen frequency in white and black

White 65% | Black 10%

FyB antigen frequency in white and black

White 80% | Black 20%

Frequency of Fy(a-b-) in white and black

White rare | Black 68%

Frequency of C in white and black

White 70% | Black 30%

Bandeira simplicifolia

B

Ulex europaeus

H

Lotus tetragonolobus

H

Arachis hypogaea

T

Vicea graminea

N