Heme Path 2

Question 1

MPO stains

Answer 1

primary (azurophilic) granules of grans

Question 2

sudan black stains

Answer 2

lipid in grans and monos

Question 3

chloroacetate esterase

Answer 3

only stains grans

Question 4

NSE

Answer 4

monocytes (inhibited by NaF)

Question 5

PAS

Answer 5

“block” positivity in ALL

diffusely granular in AML

Question 6

Pro-B phenotype

Answer 6

34
TdT
DR
19
10

Question 7

Pre-B phenotype

Answer 7

DR
19
10
20
cytoplasmic mu

Question 8

prothymocytes

Answer 8

34
TdT
2
7

Question 9

thymocytes

Answer 9

TdT
1
2
c3
5
7
4+8

Question 10

mature thymocytes

Answer 10

TdT neg
CD1 neg
4 or 8

Question 11

nk cell markers

Answer 11

16 + 56

Question 12

mono markers

Answer 12

CD11b, 15, 64, 14

Question 13

t(2;5)

Answer 13

anaplastic large cell lymphoma

ALK +

Question 14

Cyclin D1

Answer 14

(BCL-1)
Mantle cell lymphoma
Myeloma

Question 15

germinal center markers

Answer 15

BCL6, CD10

Question 16

CD1a + in

Answer 16

Langerhans cells
dendritic reticulum cells
interdigitating reticulum cells
cortical thymocytes

Question 17

normal CD4/CD8 ratio

Answer 17

2-6:1

Question 18

condition with increased circulating CD5+ B cells

Answer 18

RA

Question 19

Neoplasms with CD11c

Answer 19

CLL

Hairy cell

Question 20

other name for CD15

Answer 20

Leu-M1

Question 21

CD15 in anaplastic large cell lymphoma

Answer 21

negative

Question 22

AML with CD19 expression

Answer 22

classic for AML with t(8;21)

Question 23

CD25 is also

Answer 23

IL-2 receptor

Question 24

CD25+ in

Answer 24

Hairy cell

adult T-cell leukemia/lymphoma

Question 25

CD30 seen in (5)

Answer 25

``` plasma cells RS cells embryonal CA anaplastic large cell lymphoma mediastinal large B cell lymphoma ```

Question 26

CD38 signals aggressiveness of

Answer 26

CLL/SLL

Question 27

Mega markers

Answer 27

CD41, CD61

Question 28

CD43 expressed on B cells in (3)

Answer 28

Mantel cell lymphoma CLL/SLL marginal zone lymphoma

Question 29

CD45-RO seen on

Answer 29

T cellsq

Question 30

Sensitive and specific for Hairy cell

Answer 30

CD103