chemotoxicity amelioration

Question 1

what are the uses of amifostine ?

Answer 1

used to prevent fanconis syndrome from platinum compounds
cleans up the free radicals

Question 2

what is the use of dexrazoxane ?

Answer 2

iron chelator used for the cardiotoxicity associated from anthracyclines

Question 3

what are the uses of leucovorin ?

Answer 3

tetrahydrofolate precursor that is used for when myelosuppression happens from methotrexate
enhances the effect of 5 FU

Question 4

what are the uses of mesna ?

Answer 4

binds to acrolein
hemorrhagic cystitis from cyclophophamide

Question 5

what are the uses of rasburicase ?

Answer 5

allows for the conversion of uric acid to allantoin
used in TLS

Question 6

what is used for delayed nause and vomiting in association with chemotherapy ?

Answer 6

NK1 receptor antagonist
aprepitant

Question 7

what are the uses of filgrastim ?

Answer 7

recombinan M CSF , for neutropenia

Question 8

what are the uses of epoetin alfa ?

Answer 8

recombinant erythropoeitin for anemia