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M2M Unit III > Cholera > Flashcards

Flashcards in Cholera Deck (9)
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1

Constitutive cAMP production leads to secretion of H2O, Na+, K+, Cl−, and HCO3− into the lumen of the small intestine and _____.

rapid dehydration

2

The cholera toxin (CTX or CT) is an oligomeric complex made up of ___ protein subunits.

6

3

The _____ is an oligomeric complex made up of six protein subunits.

cholera toxin (CTX or CT)

3

In cholera, the A1 subunit of CTX binds to the ____, causing constitutive production of cAMP.

GPCR

4

In cholera, the ____ of CTX binds to the GPCR, causing constitutive production of cAMP.

A1 subunit

5

Constitutive cAMP production leads to secretion of _____ into the lumen of the small intestine and rapid dehydration.

H2O, Na+, K+, Cl−, and HCO3−

6

Cholera can be successfully treated with ___.

oral rehydration therapy (ORT)

8

In cholera, the A1 subunit of CTX binds to the GPCR, causing ______ of cAMP.

constitutive production

9

______leads to secretion of H2O, Na+, K+, Cl−, and HCO3− into the lumen of the small intestine and rapid dehydration.

Constitutive cAMP production