Clinical Bacteriology Flashcards Preview

First Aid: Microbiology > Clinical Bacteriology > Flashcards

Flashcards in Clinical Bacteriology Deck (67):
1

Staphylococcus aureus causes....

  • Inflammatory disease
  • Toxin-mediated disease
  • MRSA infection 

2

How does Toxic Shock Syndrome (S. aureus) present?

  • Fever
  • Vomiting 
  • Rash
  • Desquamation
  • Shock
  • End-organ failure 

3

Staphylococcus epidermidis infects....

prosthetic devices & intravenous catheters 

4

___________ is the 2nd most common cause of uncomplicated UTI in young women. 

Staphylococcus saprophyticus 

5

Streptococcus pneumoniae causes....

MOPS

  • Meningitis
  • Otitis media (children)
  • Pneumonia 
  • Sinusitis 

6

Viridan's group streptococci causes...

  • dental caries (Streptococcus mutans)
  • subacute bacterial endocarditis (S. sanguinis) 

7

Streptococcus pyogenes (group A) causes....

  • Pyogenic
    • pharyngitis, cellulitis, impetigo 
  • Toxigenic
    • scarlet fever, toxic shock-like syndrome, necrotizing fasciitis 
  • Immunologic 
    • rheumatic fever, acute glomerulonephritis

8

J(<3)NES criteria for rheumatic fever 

  • Joints - polyarthritis 
  • <3 - carditis 
  • Nodules (subq)
  • Erythema marginatum 
  • Sydenham chorea

9

Scarlet fever triad 

  • Scarlet rash w/ sandpaper-like texture
  • Strawberry tongue 
  • Circumoral pallor 

10

Streptococcus agalactiae (group B) causes....

mainly in babies 

  • pneumonia
  • meningitis
  • sepsis

11

Enterococci (group D) causes...

  • UTI
  • biliary tract infections
  • subacute endocarditis 

12

Streptococcus bovis (group D) causes....

  • colonizes the gut 
  • bacteremia & subacute endocarditis 
  • colon cancer patients 

13

Symptoms of Corynebacterium diphtheriae 

  • pseudomembranous pharyngitis (gray-white membrane)
  • lymphadenopathy 
  • myocarditis 
  • arrhythmias 

14

Corynebacterium diphtheriae pneumonic 

ABCDEFG

  • ADP-ribosylation
  • Beta-prophage 
  • Corynebacterium
  • Diphtheriae 
  • Elongation Factor 2
  • Granules 

15

_________ causes spastic paralysis. 

_________causes flaccid paralysis. 

Clostridium tetani

Clostridium botulinum 

16

reheated rice syndrome

Bacillus cereus 

17

the only gram (+) organism to produce LPS

Listeria monocytogenes 

18

What kind of TB?

  • Ghon focus (mid-zone of lung)
  • Fibrocaseous cavity lesion (upper lobes)

  • Primary TB
  • Secondary TB

19

What are the 4 classic symptoms of TB?

  • Fever
  • Night sweats
  • Weight loss
  • Hemoptysis 

20

What are the 2 forms of Hansen disease?

How do they differ?

  • Lepromatous
    • Leonine (lion-like) facies
    • Low cell-mediated immunity
    • Humoral Th2 response 
  • Tuberculoid
    • Hypoesthetic, hairless skin plaques
    • High cell-mediated immunity
    • Th1 type immune response 

21

Haemophilus pneumonic 

HaEMOPhilus

  • Epiglottitis
    • "cherry red" in children 
  • Meningitis
  • Otitis media
  • Pneumonia 

22

How do you culture Legionella?

use silver stain --> grow on charcoal yeast extract culture w/ iron & cysteine

 

23

Definitions

  • Legionnaire's disease
  • Pontiac fever 

  • Legionnaire's disease
    • Severe pneumonia 
    • Fever
    • GI & CNS symptoms 
  • Pontiac fever
    • Mild flu-like syndrome 

24

Pseudomonas pneumonic 

PSEUDOmonas 

  • Pneumonia (CF)
  • Sepsis
  • External otitis
  • UTI
  • Drug use
  • Diabetic Osteomyelitis 

25

Ecthyma gangrenosum

  • rapidly progressive necrotic cutaneous lesions caused by Pseudomonas bacteremia 
  • immunocompromised patients 

26

E. coli virulence factors 

  • Fimbriae - cystitis & pyelonephritis 
  • K capsule - pneumoni, neonatal meningitis 
  • LPS endotoxin - septic shock 

27

EIEC

  • Toxin & Mechanism 
  • Presentation 

  • invades intestinal mucosa
  • necrosis & inflammation
  • invasive, dysentery 

28

ETEC

  • Toxin & Mechanism
  • Presentation

  • heat-labile & heat-stable enterotoxins 
  • traveler's diarrhea (watery) 

29

EPEC

  • Toxin & Mechanism 
  • Presentation 

  • adheres to apical surface
  • flattens villi, prevents absorption
  • diarrhea in children (Pediatrics)

30

EHEC

  • Toxin & Mechanism
  • Presentation 

  • O157:H7 is the most common serotype 
  • Hemolytic Uremic Syndrome
    • Anemia 
    • Thrombocytopenia 
    • Acute renal failure 
  • dysentery, doesn't ferment sorbitol 

31

The 4 A's of Klebsiella 

  • Aspiration pneumonia
  • Abscess in lungs & liver
  • Alcoholics
  • di-A-betics 

32

Typhoid fever

  • Cause
  • Characteristics 

Salmonella typhi

  • rose spots on the abdomen 
  • fever
  • headache
  • diarrhea

33

major cause of bloody diarrhea in children 

Campylobacter jejuni 

34

Leptospirosis

  • Cause
  • Characteristics 

Leptospira interrogans 

  • flu-like symptoms
  • jaundice
  • photophobia w/ conjunctival suffusion
    • erythema w/o exudate 

35

Weil disease

 

  • icterohemorrhagic leptospirosis 
  • severe from w/ jaundice & azotemia from liver & kidney dysfunction
  • fever, hemorrhage & anemia 

36

Lyme disease pneumonic 

FAKE a Key Lyme pie 

  • Facial nerve palsy (bilateral)
  • Arthritis
  • Kardiac block
  • Erythema migrans 

37

primary syphilis 

painless chancre 

38

secondary syphilis 

  • secondary = systemic
  • constitutional symptoms
  • maculopapular rash (palms/soles)
  • condylomata lata

39

tertiary syphilis 

  • gummas (chronic granulomas)
  • aortitis (vasa vasorum destruction) 
  • neurosyphilis (tabes dorsalis)
  • Argyll Robertson pupil 

40

congenital syphilis 

  • saber shins
  • saddle nose
  • CN VIII deafness
  • Hutchinson teeth
  • mulberry molars

41

Argyll Robertson pupil 

constricts w/ accommodation

not reactive to light 

42

Anaplasmosis 

Anaplasma spp. 

43

Cat scratch disease 

Bartonella spp.

44

Lyme disease

Borrelia burgdorferi 

45

relapsing fever

Borrelia recurrentis 

46

Brucellosis/undulant fever

Brucella spp.

47

bloody diarrhea

Campylobacter 

48

Psittacosis 

Chlamydophila psittaci 

49

Q fever

Coxiella burnetii 

50

Ehrlichiosis 

Ehrlichia chaffeensis

51

Tularemia 

Francisella tularensis 

52

Leptospirosis 

Leptospira spp.

53

Leprosy 

Mycobacterium leprae 

54

cellulitis, osteomyelitis 

Pasteurella multocida 

55

Epidemic typhus 

Rickettsia proawazekii 

56

Rocky Mountain Spotted Fever

Rickettsia rickettsii

57

Endemic typhus 

Rickettsia typhi 

58

Plague

Yersinia pestis 

59

fishy smell

clue cells

vaginosis 

Garderella vaginalis 

60

Rash

  • Rocky Mountain spotted fever
  • Typhus

  • Rocky Mountain spotted fever
    • starts at wrists & ankles 
    • spreads to trunk, palms, soles
  • Typhus
    • starts centrally & spreads out
    • spares palms & soles 

61

  • monocytes w/ morulae in cytoplasm
  • granulocytes w/ morulae in cytoplasm 

  • Ehrliciosis
  • Anaplasmosis 

62

2 forms of Chlamydiae 

  • Elementary body
    • "Enfectious"
    • Enters cell via Endocytosis 
  • Reticulate body 
    • Replicates in cell by fission

63

frequent outbreaks in military recruits & prisons 

Mycoplasma pneumoniae 

64

burn victims 

Pseudomonas aeruginosa 

65

red "currant jelly" sputum 

Klebsiella 

66

Jarisch-Herxheimer reaction

flu-like syndrome after antibiotics are started

due to killed bacteria releasing pyogenes 

67

classic triad of Rocky Mountain spotted fever 

  • headache
  • fever
  • rash (vasculitis)