clinical research Flashcards

(42 cards)

1
Q

GI structures (8)

A

oesophagus, stomach, duodenum, ileum, jejunum, ascending colon, transverse colon, descending colon

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2
Q

primary germ layers (3)

A

endoderm, mesoderm, ectoderm

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3
Q

endoderm becomes (2)

A

epithelium and associated glands

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4
Q

mesoderm becomes (4)

A

mesentery, connective tissue, smooth muscle, blood vessels

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5
Q

another name for mesoderm cells

A

splanchnic

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6
Q

ectoderm becomes

A

enteric nervous system

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7
Q

another name for ectoderm cells

A

neural crest cells

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8
Q

GI tract layers (5)

A

submucosa, submucosal plexus, circular muscle, myenteric plexus, longitudinal muscle

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9
Q

mouth salivary enzymes function (2)

A

carbohydrate breakdown and start digestion

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10
Q

salivary glands role (3)

A

moisten food, lubricate food, commence digestion

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11
Q

salivary enzyme

A

amylase

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12
Q

pharynx role (2)

A

food to stomach and prervent choking

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13
Q

oeophagus role

A

food to stomach from mouth

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14
Q

stomach secretes (2)

A

gastric juices and hydrochloric acid

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15
Q

stomach role (4)

A

digest food, kill pathogens, store food, churn food

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16
Q

stomach enzyme to break down protein

A

pepsin

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17
Q

largest organ in the body

18
Q

liver role (7)

A

produce bile, food into energy, clear alcohol, clear some medicines, clear poison from blood, store vitamin and iron, destroy old blood cells

19
Q

bile (2)

A

breaksdown fat and removes waste from body

20
Q

gallbladder role

21
Q

gallbladder secretes bile into

A

small intestine

22
Q

where can stones form

23
Q

pancreas role (3)

A

digestive enzyme production, bicarbonate production to neutralise stomach acid, insulin production

24
Q

what does nuerourology study

A

dysregulation and injury/degenerration

25
what can dysregulate the urinary system (7)
overactive, underactive bladder, chronic inflammation, urinary incontinence, retention, visceral and pelvic pain, ageing
26
what can cause urinary injury and degeneration (7)
pelvic surrgery, spinal cord injuries/neurogenic bladder, diabetic neuropathy, stoke, MS, parkinsons, alzeihmers
27
sub topics of neurourology (5)
neural origin, neural contributors, symptoms, progression, solutions
28
teams that works with neurourology (6)
urology, gynecology, neurology, immunology, neurobiology, engineering
29
scope of challenge (4)
brain, spinal cord, sensory and autonomic ganglia, nerve genitourinary organ interface
30
what types of disease has vagal neuromodulation been used for (6)
cardiac, immune, metabolic, CNS, GI, respiratory
31
immune diseases using vagal neuromodulation (2)
Crohn's and RA
32
metabolic diseases using vagal neuromodulation (2)
obesity and T2D
33
CNS diseases using vagal neuromodulation (3)
epilepsy, depression, migraines
34
SPARC
stimulating peripheral activity to relieve conditions
35
what does SPARC use (5)
neural maps, computational models, electrode design, stimulation protocols, surgical methods
36
what does the pelvic nerve supply (2)
majority of lower urinary tract and multiple organs
37
LUT
lower urinary tract
38
pelvic nerve human analogue
pelvic splanchnic nerve
39
pelvic nerve speecifically supplies (4)
bladder contractions, urethra relaxation, mechanosensors, nociceptors
40
what does multi scale mapping do (4)
cell to organ structure and function, comparing biological life cycles, cross species harmonisation, micro to macro
41
underlying reference map contextualising new samples
common coordinate framework
42
complete map of neural connections
connectome